SCHEMBL9329236

SCHEMBL9329236

NCCCCCCCCCCCCCCCCCC(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.52
MMP2 P08253 2/20 0.48
CPB2 Q96IY4 2/20 0.46
HTR2A P28223 3/20 0.45
HRH1 P35367 1/20 0.45
EPHX1 P07099 1/20 0.45
CSNK1E P49674 1/20 0.44
TAAR1 Q96RJ0 3/20 0.42
SLC6A2 P23975 2/20 0.42
CYP2A6 P11509 2/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
ADORA2A P29274 1/20 0.42
ADORA1 P30542 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28713654 1.00 MAOA (0.52) MAOAMMP2CPB2HTR2AHRH1
SCHEMBL8086703 1.00 MAOA (0.52) MAOAMMP2CPB2HTR2AHRH1
SCHEMBL27893436 1.00 MAOA (0.52) MAOAMMP2CPB2HTR2AHRH1
SCHEMBL11094964 1.00 MAOA (0.52) MAOAMMP2CPB2HTR2AHRH1
SCHEMBL11097972 1.00 MAOA (0.52) MAOAMMP2CPB2HTR2AHRH1
SCHEMBL8664619 0.92 HTR2A (0.54) MAOAMMP2HTR2AHRH1EPHX1
Toluene SCHEMBL11877370 0.91 MAOA (0.44) MAOAMMP2CPB2HTR2AHRH1
SCHEMBL24108632 0.89 EPHX1 (0.48) MAOAEPHX1CSNK1ETAAR1SLC6A2
SCHEMBL11662542 0.84 CPA3 (0.55) MMP2CPB2
SCHEMBL11145503 0.83 EPHX1 (0.52) MAOAHTR2AHRH1EPHX1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0383089-B1 Cold curing reactive resin blend and its use BAYER AG (DE) 1994-04-06 EP claimed
US-5084544-A Reaction of polyepoxides and polyisocyanates to form polyurethanes BAYER AKTIENGESELLSCHAFT (DE) 1992-01-28 US claimed
US-4450114-A Process for production of sulfuric acid semiesters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-05-22 US claimed
US-4351765-A Process for the production of compounds having in the molecule at least one β-sulfatoethyl-sulfone group and at least one sulfonic acid group SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-09-28 US claimed
US-4450114-A Process for production of sulfuric acid semiesters SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-05-22 US disclosed
US-4351765-A Process for the production of compounds having in the molecule at least one β-sulfatoethyl-sulfone group and at least one sulfonic acid group SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-09-28 US disclosed