Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131204 | 0.93 | DHPS (0.47) | DHPSMEN1KMT2ANPC1HDAC1 | |
| Hydrochloric Acid SCHEMBL9130882 | 0.90 | DHPS (0.48) | DHPSMEN1KMT2ANPC1HSD17B10 | |
| SCHEMBL9132823 | 0.88 | DHPS (0.50) | DHPSMEN1KMT2ANPC1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9132778 | 0.87 | DHPS (0.49) | DHPSMEN1KMT2ANPC1HSD17B10 | |
| SCHEMBL9136237 | 0.85 | DHPS (0.47) | DHPSMEN1KMT2ANPC1HDAC1 | |
| SCHEMBL10413109 | 0.84 | DHPS (0.47) | DHPSMEN1KMT2ANPC1HSD17B10 | |
| SCHEMBL9130336 | 0.83 | DHPS (0.50) | DHPSMEN1KMT2ANPC1HDAC1 | |
| SCHEMBL9130186 | 0.83 | HTR1B (0.60) | DHPSMEN1KMT2ANPC1HSD17B10 | |
| SCHEMBL10413108 | 0.83 | HTR1B (0.52) | DHPSMEN1KMT2ANPC1HSD17B10 | |
| SCHEMBL9132310 | 0.83 | MEN1 (0.50) | DHPSMEN1KMT2ANPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380722-A | Antiarrhythmia agents | ROUSSEL-UCLAF (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5084455-A | Antiarrhythmia agents for mammals | ROUSSEL UCLAF (FR) | 1992-01-28 | — | — | US | disclosed |
| US-4908367-A | Antiarrythmic agents | Uclaf, Roussel (FR) | 1990-03-13 | — | — | US | disclosed |