Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 4/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132566 | 0.97 | DHPS (0.49) | DHPSRXFP1HDAC3HDAC1BRD4 | |
| SCHEMBL9133428 | 0.97 | DHPS (0.51) | DHPSRXFP1HDAC3HDAC1BRD4 | |
| Hydrochloric Acid SCHEMBL9739316 | 0.96 | DHPS (0.50) | DHPSRXFP1HDAC3HDAC1BRD4 | |
| SCHEMBL9131204 | 0.91 | DHPS (0.47) | DHPSRXFP1HDAC3HDAC1BRD4 | |
| SCHEMBL9136237 | 0.91 | DHPS (0.47) | DHPSRXFP1HDAC3HDAC1BRD4 | |
| Hydrochloric Acid SCHEMBL9130882 | 0.91 | DHPS (0.48) | DHPSRXFP1HDAC3HDAC1BRD4 | |
| SCHEMBL9132823 | 0.89 | DHPS (0.50) | DHPSRXFP1HDAC3HDAC1BRD4 | |
| SCHEMBL9132463 | 0.88 | HTR1A (0.44) | HTR1BDRD4DRD3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9132778 | 0.88 | DHPS (0.49) | DHPSRXFP1HDAC3HDAC1BRD4 | |
| SCHEMBL9132886 | 0.86 | HTR1A (0.48) | DHPSRXFP1HDAC3HDAC1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084455-A | Antiarrhythmia agents for mammals | ROUSSEL UCLAF (FR) | 1992-01-28 | — | — | US | claimed |
| EP-0213984-B1 | INDOLE CARBOXAMIDE DERIVATIVES, THEIR SALTS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1991-01-09 | — | — | EP | claimed |
| US-4791109-A | Novel indole carboxamides | ROUSSEL UCLAF (FR) | 1988-12-13 | — | — | US | claimed |
| US-5380722-A | Antiarrhythmia agents | ROUSSEL-UCLAF (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5084455-A | Antiarrhythmia agents for mammals | ROUSSEL UCLAF (FR) | 1992-01-28 | — | — | US | disclosed |
| US-4908367-A | Antiarrythmic agents | Uclaf, Roussel (FR) | 1990-03-13 | — | — | US | disclosed |
| US-4791109-A | Novel indole carboxamides | ROUSSEL UCLAF (FR) | 1988-12-13 | — | — | US | disclosed |