Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.40 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.40 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11316947 | 0.97 | FKBP5 (0.39) | CRBNFKBP5OTUD7BOR51E2GRIN1 | |
| SCHEMBL6673999 | 0.97 | FKBP5 (0.39) | CRBNFKBP5OTUD7BOR51E2GRIN1 | |
| SCHEMBL5173578 | 0.95 | OTUD7B (0.37) | CRBNFKBP5OTUD7BOR51E2GRIN1 | |
| SCHEMBL2171976 | 0.92 | GRIN1 (0.40) | CRBNFKBP5OTUD7BOR51E2GRIN1 | |
| SCHEMBL21224581 | 0.91 | CRBN (0.38) | CRBNFKBP5OTUD7BOR51E2GRIN1 | |
| SCHEMBL25238524 | 0.90 | OTUD7B (0.37) | CRBNFKBP5OTUD7BOR51E2GRIN1 | |
| SCHEMBL1429855 | 0.90 | OTUD7B (0.46) | CRBNOTUD7BGRIN1GRIN2AGRIN2B | |
| SCHEMBL15018071 | 0.90 | — | — | |
| SCHEMBL22958822 | 0.89 | CRBN (0.37) | CRBNFKBP5OTUD7BOR51E2GRIN1 | |
| SCHEMBL4829 | 0.87 | OTUD7B (0.44) | CRBNOTUD7BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393592-A | A coextruded multilayer thermoplastic styrene resins, free of protective coatings; impact strength, high melting; seals | BASF AKTIENGESELLSCHAFT (DE) | 1995-02-28 | — | — | US | disclosed |