Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CKS1B | P61024 | 1/20 | 0.52 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 6/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128626 | 0.94 | ALDH1A1 (0.55) | HPGDTP53CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL4418335 | 0.86 | TYR (0.57) | TP53CYP3A4ALOX15MEN1ALOX5 | |
| SCHEMBL9129252 | 0.85 | CYP4F2 (0.56) | HPGDTP53CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL27810348 | 0.84 | HPGD (0.42) | HPGDTP53CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL10602853 | 0.83 | TP53 (0.47) | HPGDTP53CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL8764365 | 0.83 | TYR (0.59) | TP53CYP3A4ALOX15MEN1ALOX5 | |
| SCHEMBL3838231 | 0.82 | F13A1 (0.59) | HPGDTP53CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL2381980 | 0.82 | F13A1 (0.59) | HPGDTP53CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL4148828 | 0.82 | F13A1 (0.59) | HPGDTP53CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL3840098 | 0.82 | F13A1 (0.59) | HPGDTP53CYP3A4ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449518-A | Bleaching, decoloring skin | L'OREAL (FR) | 1995-09-12 | — | — | US | claimed |
| US-5449518-A | Bleaching, decoloring skin | L'OREAL (FR) | 1995-09-12 | — | — | US | disclosed |