Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.76 |
| ▸ | MAOA | P21397 | 3/20 | 0.76 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.76 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL963148 | 1.00 | MAOB (0.76) | MAOBMAOASCN9AGRM5PPARA | |
| SCHEMBL964081 | 0.91 | MAOB (0.63) | MAOBMAOASCN9A | |
| SCHEMBL14329886 | 0.87 | MAOB (0.81) | MAOBMAOASCN9AGRM5PPARA | |
| SCHEMBL2933427 | 0.87 | MAOB (0.81) | MAOBMAOASCN9APPARA | |
| SCHEMBL2933423 | 0.87 | MAOB (0.81) | MAOBMAOASCN9APPARA | |
| SCHEMBL7395880 | 0.87 | MAOB (0.64) | MAOBMAOASCN9AGRM5PPARA | |
| SCHEMBL8935295 | 0.87 | MAOB (0.64) | MAOBMAOASCN9AGRM5PPARA | |
| SCHEMBL8935307 | 0.87 | ALOX5 (0.60) | MAOBMAOASCN9A | |
| Safinamide SCHEMBL69350 | 0.86 | MAOB (1.00) | MAOBMAOASCN9A | |
| Safinamide SCHEMBL194169 | 0.86 | MAOB (1.00) | MAOBMAOASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391577-A | Active on central nervous system; antiepileptic agents | FARMITALIA CARLO ERBA S R L (IT) | 1995-02-21 | — | — | US | disclosed |
| US-5236957-A | Antiepileptic agents | FARMITALIA CARLO ERBA SRL (IT) | 1993-08-17 | — | — | US | disclosed |