Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.64 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395880 | 1.00 | MAOB (0.64) | MAOBMAOASCN9APPARANR4A2 | |
| SCHEMBL8935315 | 0.87 | ALOX5 (0.57) | MAOBMAOASCN9A | |
| SCHEMBL963148 | 0.87 | MAOB (0.76) | MAOBMAOASCN9APPARAGRM5 | |
| SCHEMBL9129586 | 0.87 | MAOB (0.76) | MAOBMAOASCN9APPARAGRM5 | |
| SCHEMBL8935359 | 0.87 | MMP9 (0.56) | MAOB | |
| SCHEMBL8935334 | 0.87 | MMP9 (0.56) | MAOB | |
| SCHEMBL1068001 | 0.86 | MAOB (0.65) | MAOBMAOASCN9APPARANR4A2 | |
| SCHEMBL7398478 | 0.86 | MAOB (0.65) | MAOBMAOASCN9APPARANR4A2 | |
| SCHEMBL31060712 | 0.86 | MAOB (0.74) | MAOBMAOASCN9APARP10 | |
| SCHEMBL963815 | 0.86 | MAOB (0.74) | MAOBMAOASCN9APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |
| US-5391577-A | Active on central nervous system; antiepileptic agents | FARMITALIA CARLO ERBA S R L (IT) | 1995-02-21 | — | — | US | disclosed |
| US-5236957-A | Antiepileptic agents | FARMITALIA CARLO ERBA SRL (IT) | 1993-08-17 | — | — | US | disclosed |