SCHEMBL9129588

SCHEMBL9129588

CCn1cnc2cc(C#N)c(C#N)cc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.45
MAPK1 P28482 1/20 0.45
LMNA P02545 2/20 0.41
NPC1 O15118 8/20 0.40
RAB9A P51151 7/20 0.40
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
GAA P10253 1/20 0.40
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 4/20 0.40
MAPT P10636 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
POLB P06746 2/20 0.39
HDAC1 Q13547 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
TP53 P04637 1/20 0.37
HTT P42858 1/20 0.37
GFER P55789 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9125446 0.87 PGK1 (0.47) USP2MAPK1LMNANPC1RAB9A
SCHEMBL8876066 0.87 AR (0.43) USP2MAPK1LMNANPC1RAB9A
SCHEMBL5084482 0.87 AR (0.43) USP2MAPK1LMNANPC1RAB9A
SCHEMBL5078597 0.87 PGK1 (0.47) USP2MAPK1LMNANPC1RAB9A
SCHEMBL11331901 0.77 BRD4 (0.49) BRD4
SCHEMBL5085214 0.77 NPC1 (0.48) LMNANPC1RAB9AKMT2AMEN1
SCHEMBL24463281 0.74 PGK1 (0.46) LMNANPC1RAB9AKMT2AMEN1
SCHEMBL30263484 0.74 PGK1 (0.46) LMNANPC1RAB9AKMT2AMEN1
SCHEMBL26790579 0.74 GGPS1 (0.43) LMNANPC1RAB9AKMT2AMEN1
SCHEMBL7854588 0.74 LMNA (0.69) LMNANPC1RAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5382497-A Optical recording medium and process for recording thereupon CANON KABUSHIKI KAISHA (JP) 1995-01-17 US disclosed
US-5320930-A Irradiating to form detectable pits; containing pyrylium, cyanine, merocyanine dyes, selenapyrylium and methine dyes CANON KABUSHIKI KAISHA (JP) 1994-06-14 US disclosed
US-5278026-A Comprising photosensitive compounds CANON KABUSHIKI KAISHA (JP) 1994-01-11 US disclosed
US-5246814-A Mehtine or pyrylium dye CANON KABUSHIKI KAISHA (JP) 1993-09-21 US disclosed
EP-0264198-B1 OPTICAL INFORMATION RECORDING MEDIUM CANON KABUSHIKI KAISHA (JP) 1993-03-03 EP disclosed
US-5190849-A Heat and light stability CANON KABUSHIKI KAISHA (JP) 1993-03-02 US disclosed
US-5187043-A Improved stability to light and heat, high sensitivity, great absorption and high reflection characteristics at the long wavelength side CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5178995-A Reflectance, storage stability CANON KABUSHIKI KAISHA (JP) 1993-01-12 US disclosed
US-5079127-A Methine Dyes CANON KABUSHIKI KAISHA (JP) 1992-01-07 US disclosed
US-5079128-A Thin film containing a methine dye having at least two dimethylaminophenyl groups and a carbonium ion; laser writing; heat resistance CANON KABUSHIKI KAISHA (JP) 1992-01-07 US disclosed
US-5004671-A Diacetylene compound and azulenium salt, diene compound, or croconic methine compound CANON KABUSHIKI KAISHA (JP) 1991-04-02 US disclosed
US-4910107-A Irradiating with ultraviolet radiation; then infrared radiation CANON KABUSHIKI KAISHA (JP) 1990-03-20 US disclosed
US-4891305-A LASERS RICOH CO., LTD. (JP) 1990-01-02 US disclosed
US-4863832-A Optical recording employing diacetylene compound and dye to change color and form pits CANON KABUSHIKI KAISHA (JP) 1989-09-05 US disclosed
US-4782006-A IRRADIATION POLYMERIZATION CANON KABUSHIKI KAISHA (JP) 1988-11-01 US disclosed
EP-0264198-A2 Optical information recording medium CANON KABUSHIKI KAISHA (JP) 1988-04-20 EP disclosed
US-4555472-A OPTICAL RECORDING MEDIA CANON KABUSHIKI KAISHA (JP) 1985-11-26 US disclosed