SCHEMBL9129646

SCHEMBL9129646

CCSCC1=CCN(C)CC1

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
QDPR P09417 2/20 0.36
SIGMAR1 Q99720 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9130804 0.86 SIGMAR1 (0.43) QDPRSIGMAR1
SCHEMBL9130250 0.81 QDPR (0.38) QDPRSIGMAR1
SCHEMBL9129212 0.80 KDM4E (0.35)
SCHEMBL7607024 0.78
SCHEMBL9644027 0.75 QDPR (0.39) QDPRSIGMAR1
SCHEMBL15370330 0.72
SCHEMBL6953079 0.72
SCHEMBL4700734 0.72
SCHEMBL14311964 0.72
SCHEMBL9129304 0.72 QDPR (0.41) QDPRSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5422353-A Alzheimer*s disease, glaucoma treatment BOEHRINGER INGELHEIM KG (DE) 1995-06-06 US disclosed
EP-0325263-B1 TETRAHYDROPYRIDINE DERIVATIVES BOEHRINGER INGELHEIM KG (DE) 1992-09-23 EP disclosed
US-5136042-A PROCESS FOR THE PREPARATION OF THIAZOLECARBOXYLIC ACID CHLORIDES MITSUI TOATSU CHEMICALS, INC. (JP) 1992-08-04 US disclosed
EP-0377750-A1 PROCESS FOR PREPARING THIAZOLECARBOXYLIC ACID CHLORIDES MITSUI CHEMICALS, INC. (JP) 1990-07-18 EP disclosed
EP-0325263-A1 Tetrahydropyridine derivatives BOEHRINGER INGELHEIM KG (DE) 1989-07-26 EP disclosed