SCHEMBL9129657

SCHEMBL9129657

O=C(Oc1ccc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)c2ccc(OC(=O)c3ccc(C(=O)O)c(C(=O)O)c3)cc2)cc1)c1ccc(C(=O)O)c(C(=O)O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
MAPT P10636 2/20 0.41
PRSS1 P07477 1/20 0.41
ACR P10323 1/20 0.41
POLB P06746 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 3/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
USP2 O75604 1/20 0.39
CYP2C19 P33261 1/20 0.39
CDC25A P30304 1/20 0.39
CDC25B P30305 1/20 0.39
HPSE Q9Y251 1/20 0.38
APEX1 P27695 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9132415 1.00 L3MBTL1 (0.41) L3MBTL1TDP1MAPTPRSS1ACR
SCHEMBL9131432 1.00 L3MBTL1 (0.41) L3MBTL1TDP1MAPTPRSS1ACR
SCHEMBL9129524 0.96 L3MBTL1 (0.42) L3MBTL1TDP1MAPTPRSS1ACR
SCHEMBL11013764 0.88 PRSS1 (0.37) L3MBTL1TDP1MAPTPRSS1ACR
SCHEMBL10442499 0.86 PRSS1 (0.39) L3MBTL1TDP1MAPTPRSS1ACR
SCHEMBL10442448 0.85 L3MBTL1 (0.40) L3MBTL1TDP1MAPTPRSS1ACR
SCHEMBL31541190 0.85 L3MBTL1 (0.42) L3MBTL1TDP1MAPTPRSS1ACR
SCHEMBL4412401 0.85 L3MBTL1 (0.42) L3MBTL1TDP1MAPTPRSS1ACR
SCHEMBL9129348 0.84 L3MBTL1 (0.40) L3MBTL1TDP1MAPTPRSS1ACR
SCHEMBL11848517 0.84 HSD17B10 (0.52) L3MBTL1TDP1MAPTPRSS1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 EP claimed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US claimed
EP-0400635-A2 Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1990-12-05 EP claimed
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 EP disclosed
US-5426525-A Ferroelectric smectic liquid crystal device CANON KABUSHIKI KAISHA (JP) 1995-06-20 US disclosed
EP-0373952-B1 Photosensitive resin composition and photosensitive element using the same HITACHI CHEMICAL CO LTD (JP) 1995-02-08 EP disclosed
EP-0142149-B1 Use of fluorine containing polyimides for aligning layers of liquid crystal display devices. HITACHI LTD (JP) 1995-02-01 EP disclosed
US-5316805-A Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1994-05-31 US disclosed
US-5262277-A Light sensitive elements for electrical thick films with heat resistance HITACHI CHEMICAL COMPANY, INC. (JP) 1993-11-16 US disclosed
EP-0219336-B1 LIQUID CRYSTAL ORIENTATION CONTROLLING FILM AND LIQUID CRYSTAL DEVICE USING THE SAME Hitachi Chemical Co., Ltd. (JP) 1993-07-21 EP disclosed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US disclosed
EP-0373952-A2 Photosensitive resin composition and photosensitive element using the same Hitachi Chemical Co., Ltd. (JP) 1990-06-20 EP disclosed
US-4760126-A Fluorine-containing polyamide-acid derivative and polyimide HITACHI, LTD. (JP) 1988-07-26 US disclosed
US-4735492-A POLYIMIDE-ISOIDOLOQUINAZOLINEDIONE HITACHI CHEMICAL COMPANY, LTD. (JP) 1988-04-05 US disclosed
EP-0219336-A2 Liquid crystal orientation controlling film and liquid crystal device using the same Hitachi Chemical Co., Ltd. (JP) 1987-04-22 EP disclosed