SCHEMBL9129690

SCHEMBL9129690

COc1ccc(OCc2ccc(C=O)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.69
NPC1 O15118 2/20 0.69
TDP1 Q9NUW8 1/20 0.69
ALDH1A1 P00352 3/20 0.68
CYP2A6 P11509 1/20 0.68
APP P05067 5/20 0.61
MAOB P27338 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.58
POLB P06746 1/20 0.58
HPGD P15428 2/20 0.57
MAPT P10636 2/20 0.56
LMNA P02545 1/20 0.56
FFAR1 O14842 2/20 0.55
HTT P42858 1/20 0.54
PTPN1 P18031 1/20 0.53
PPARG P37231 1/20 0.53
PPARD Q03181 1/20 0.53
PPARA Q07869 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL864643 1.00 RAB9A (0.69) RAB9ANPC1TDP1ALDH1A1CYP2A6
SCHEMBL23223734 0.91 RAB9A (0.69) RAB9ANPC1TDP1ALDH1A1CYP2A6
SCHEMBL11614936 0.91 RAB9A (0.69) RAB9ANPC1TDP1ALDH1A1CYP2A6
SCHEMBL19209511 0.87 ALDH1A1 (0.70) RAB9ANPC1TDP1ALDH1A1CYP2A6
SCHEMBL864257 0.86 MAOB (0.67) RAB9ANPC1TDP1ALDH1A1CYP2A6
SCHEMBL13462927 0.86 SMN1; SMN2 (0.75) RAB9ANPC1TDP1ALDH1A1CYP2A6
SCHEMBL4054280 0.86 SMN1; SMN2 (0.75) RAB9ANPC1TDP1ALDH1A1CYP2A6
SCHEMBL4056179 0.86 MAOB (0.67) RAB9ANPC1TDP1ALDH1A1CYP2A6
SCHEMBL9607336 0.85 ALDH1A1 (0.79) RAB9ANPC1TDP1ALDH1A1CYP2A6
SCHEMBL20000873 0.84 APP (0.80) RAB9ANPC1ALDH1A1APPMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5399575-A Antiallergens BOEHRINGER MANNHEIM GMBH (DE) 1995-03-21 US disclosed