Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 4/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | ATG7 | O95352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129707 | 1.00 | TYMP (0.42) | TYMPTOP2APIM1CSNK2A2CSNK2B | |
| SCHEMBL9126597 | 0.81 | PIM1 (0.54) | PIM1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL9126599 | 0.81 | PIM1 (0.54) | PIM1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL9128612 | 0.79 | DRD2 (0.40) | DRD2SLC6A4KMT2A | |
| SCHEMBL9128609 | 0.79 | DRD2 (0.40) | DRD2SLC6A4KMT2A | |
| SCHEMBL24512397 | 0.76 | DNMT1 (0.67) | TYMPTOP2AADRB1DNMT1ATG7 | |
| SCHEMBL23371822 | 0.76 | DNMT1 (0.67) | TYMPTOP2AADRB1DNMT1ATG7 | |
| SCHEMBL20651314 | 0.76 | DNMT1 (0.67) | TYMPTOP2AADRB1DNMT1ATG7 | |
| SCHEMBL23358428 | 0.76 | DNMT1 (0.67) | TYMPTOP2AADRB1DNMT1ATG7 | |
| SCHEMBL4783238 | 0.75 | HIF1A (0.53) | TYMPHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446139-A | Purine analog nucleoside and nucleotide compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1995-08-29 | — | — | US | disclosed |