Pyrene

Pyrene

SCHEMBL9130

c1cc2ccc3cccc4ccc(c1)c2c34

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
HSD17B10 Q99714 6/20 1.00
TSHR P16473 6/20 1.00
HPGD P15428 4/20 1.00
CYP3A4 P08684 3/20 1.00
CYP1A2 P05177 3/20 1.00
CYP1A1 P04798 2/20 1.00
CYP1B1 Q16678 2/20 1.00
THRB P10828 1/20 0.59
TDP1 Q9NUW8 3/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
MAPK1 P28482 2/20 0.53
ATM Q13315 1/20 0.53
ERBB2 P04626 1/20 0.50
FYN P06241 1/20 0.50
MAOA P21397 1/20 0.50
ACHE P22303 1/20 0.50
AHR P35869 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrene SCHEMBL1332849 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL1650929 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL223412 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL29429699 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL23319293 0.96 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL21693735 0.96 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL11237257 0.96 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL4399830 0.96 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL8161789 0.96 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL4977930 0.96 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 169641 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6432632-B1 None US claimed
US-6432363-B1 None US claimed
US-20260150492-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2026-05-28 US claimed
EP-3371589-B1 INTERFACIAL NANOFIBRIL COMPOSITE FOR SELECTIVE ALKANE VAPOR DETECTION UNIV UTAH RES FOUND (US) 2026-05-27 EP claimed
US-12637536-B2 Epoxy resin composition, prepreg, fiber-reinforced resin molded body, and integrated product TORAY INDUSTRIES, INC. (JP) 2026-05-26 US claimed
CN-122094993-A Copolymer, viscosity reducer and positive electrode slurry composition containing same, positive electrode containing positive electrode slurry composition, and secondary battery comprising positive electrode 2026-05-26 CN claimed
CN-122081300-A Preparation method of nano-sized hydrogen bond organic framework immobilized carbonic anhydrase particles 2026-05-26 CN claimed
CN-122094309-A Optoelectronic device and method for producing the same 2026-05-26 CN claimed
US-12638602-B2 Metal organic framework particles as radioisotope detectors ARIZONA BOARD OF REGENTS OF BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-05-26 US claimed
CN-122094307-A Photoelectric device 2026-05-26 CN claimed
US-4001313-A MANUFACTURE OF AROMATIC AMINO COMPOUNDS OSAKA CITY (JA) 1977-01-04 US claimed
US-3990513-A Method of solution mining of coal KOPPERS COMPANY, INC. (US) 1976-11-09 US claimed
US-3970545-A Hydrocarbon desulfurization utilizing a non-catalytic hydrogen donor step and an oxidation step ATLANTIC RICHFIELD COMPANY (US) 1976-07-20 US claimed
US-3961953-A VACUUM DEPOSITION, THIN FILMS, PHOTOSENSITIVITY XEROX CORPORATION (US) 1976-06-08 US claimed
US-3960976-A COMPLEXING WITH A TRIHALOACETATE FOLLOWED BY DECOMPOSITION MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) 1976-06-01 US claimed
US-3954906-A ELECTROSTATOGRAPHIC IMAGING XEROX CORPORATION (US) 1976-05-04 US claimed
US-3954464-A Method of fabricating a composite trigonal selenium photoreceptor XEROX CORPORATION (US) 1976-05-04 US claimed
US-3943108-A Photoconductive composition of an aldehyde condensate XEROX CORPORATION (US) 1976-03-09 US claimed
US-3941750-A Polyvinylpyrenal--an intrinsic photoconductor and active matrix polymer XEROX CORPORATION (US) 1976-03-02 US claimed
US-3935009-A FLUOREN-9-YLIDENE OCE-VAN DER GRINTEN N.V. (NL) 1976-01-27 US claimed