Pyrene

Pyrene

SCHEMBL223412

c1cc2ccc3cccc4ccc(c1)c2c34.c1cc2ccc3cccc4ccc(c1)c2c34

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
HSD17B10 Q99714 6/20 1.00
TSHR P16473 6/20 1.00
HPGD P15428 4/20 1.00
CYP3A4 P08684 3/20 1.00
CYP1A2 P05177 3/20 1.00
CYP1A1 P04798 2/20 1.00
CYP1B1 Q16678 2/20 1.00
THRB P10828 1/20 0.59
TDP1 Q9NUW8 3/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
MAPK1 P28482 2/20 0.53
ATM Q13315 1/20 0.53
ERBB2 P04626 1/20 0.50
FYN P06241 1/20 0.50
MAOA P21397 1/20 0.50
ACHE P22303 1/20 0.50
AHR P35869 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrene SCHEMBL1332849 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL1650929 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL9130 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL29429699 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL23319293 0.96 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL21693735 0.96 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL11237257 0.96 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL4399830 0.96 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL8161789 0.96 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4
Pyrene SCHEMBL4977930 0.96 ALDH1A1 (0.92) ALDH1A1HSD17B10TSHRHPGDCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 663 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12041798-B2 Display panel SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-16 US disclosed
US-20240237528-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-11 US disclosed
US-12035552-B2 Organic electroluminescence device and amine compound for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-09 US disclosed
US-12035616-B2 Organic electroluminescence device and organometallic complex for organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-09 US disclosed
US-20240224793-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-04 US disclosed
US-12029109-B2 Light emitting diode and amine compound for the same SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-02 US disclosed
US-20240215286-A1 LIGHT EMITTING DEVICE AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-27 US disclosed
US-20240215445-A1 LIGHT EMITTING DEVICE AND FUSED POLYCYCLIC COMPOUND FOR THE LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-27 US disclosed
US-20240215444-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-27 US disclosed
US-20240215446-A1 LIGHT EMITTING DEVICE AND POLYCYCLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-27 US disclosed
EP-1359790-A2 Organic light-emitting diode devices with improved operational stability EASTMAN KODAK COMPANY (US) 2003-11-05 EP disclosed
CN-1453886-A Organic light-emitting diode equipment with improved operation stability EASTMAN KODAK CO (US) 2003-11-05 CN disclosed
EP-0810291-B1 PROBE FOR USE IN NUCLEIC ACID ANALYSIS AND DETECTING METHOD BASED ON EXCIMER FLUORESCENCE HAMAMATSU PHOTONICS KK (JP) 2003-10-29 EP disclosed
US-20030144185-A1 Cyclic peptide structures for molecular scale electronic and photonic devices WORCESTER POLYTECHNIC INSTITUTE 2003-07-31 US disclosed
EP-1135141-A4 PHOSPHOLIPASE INHIBITORS FOR THE TREATMENT OF CANCER ANALYTICA LTD (AU) 2003-03-05 EP disclosed
EP-1135141-A1 PHOSPHOLIPASE INHIBITORS FOR THE TREATMENT OF CANCER Analytica Ltd. (AU) 2001-09-26 EP disclosed
WO-2000028997-A1 PHOSPHOLIPASE INHIBITORS FOR THE TREATMENT OF CANCER ANALYTICA LTD (AU) 2000-05-25 WO disclosed
WO-1999029726-A1 PHOSPHOLIPASE INHIBITOR HSC (PLA) PTY. LTD. (AU) 1999-06-17 WO disclosed
EP-0810291-A1 PROBE FOR USE IN NUCLEIC ACID ANALYSIS AND DETECTING METHOD The society for Techno-Innovation of Agriculture, Forestry and Fisheries (JP) 1997-12-03 EP disclosed
US-5600958-A Shipper HENNING STEVE (US) 1997-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240215444-A1 LIGHT EMITTING ELEMENT AND POLYCYCLIC COMPOUND FOR THE SAME NFE2L2, SLC1A2, CRY1 ALDH1A1 665/4885HSD17B10 1531/4885TSHR 4010/4885
US-20030144185-A1 Cyclic peptide structures for molecular scale electronic and photonic devices VIP, NPPA, NGLY1 ALDH1A1 3571/4885HSD17B10 4665/4885TSHR 2074/4885
US-12035616-B2 Organic electroluminescence device and organometallic complex for organic electroluminescence device L1CAM, EML4, EPCAM ALDH1A1 1044/4885HSD17B10 4127/4885TSHR 3950/4885
US-20240215446-A1 LIGHT EMITTING DEVICE AND POLYCYCLIC COMPOUND FOR THE SAME TPH1, HCRTR1, HTR3D ALDH1A1 17/4885HSD17B10 1434/4885TSHR 806/4885
US-20240215445-A1 LIGHT EMITTING DEVICE AND FUSED POLYCYCLIC COMPOUND FOR THE LIGHT EMITTING DEVICE CRY1, LAGE3, LEF1 ALDH1A1 6/4885HSD17B10 1642/4885TSHR 3879/4885
US-20240224793-A1 LIGHT EMITTING ELEMENT AND AMINE COMPOUND FOR THE SAME SLC1A2, SLC18A2, SLC18A1 ALDH1A1 138/4885HSD17B10 3105/4885TSHR 1966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.