Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126781 | 0.97 | MTNR1A (0.64) | MTNR1ASMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL9490321 | 0.86 | MTNR1A (0.60) | MTNR1ASMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL9493169 | 0.85 | MTNR1A (0.60) | MTNR1ASMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL9491759 | 0.85 | SMN1; SMN2 (0.70) | MTNR1ASMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL9797192 | 0.85 | SMN1; SMN2 (0.58) | MTNR1ASMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL9493618 | 0.84 | KDM4E (0.60) | MTNR1ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL3719877 | 0.82 | SMN1; SMN2 (0.74) | MTNR1ASMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL9490706 | 0.82 | SMN1; SMN2 (0.55) | MTNR1ASMN1; SMN2KDM4ENPC1LMNA | |
| SCHEMBL9496042 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4ENPC1LMNATP53 | |
| SCHEMBL9490605 | 0.82 | SMN1; SMN2 (0.55) | MTNR1ASMN1; SMN2KDM4ENPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385944-A | Naphthylethylureas and naphthylethylthioureas | ADIR ET COMPAGNIE (FR) | 1995-01-31 | — | — | US | disclosed |