Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | FPR2 | P25090 | 4/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9126781 | 0.87 | MTNR1A (0.64) | SMN1; SMN2MAPTKDM4ENPC1LMNA | |
| SCHEMBL3719877 | 0.85 | SMN1; SMN2 (0.74) | SMN1; SMN2MAPTKDM4ENPC1LMNA | |
| SCHEMBL9130202 | 0.85 | MTNR1A (0.61) | SMN1; SMN2MAPTKDM4ENPC1LMNA | |
| SCHEMBL9491759 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2MAPTKDM4ENPC1LMNA | |
| SCHEMBL9493169 | 0.81 | MTNR1A (0.60) | SMN1; SMN2MAPTKDM4ENPC1LMNA | |
| SCHEMBL9492873 | 0.80 | MTNR1A (0.62) | SMN1; SMN2MAPTKDM4ENPC1LMNA | |
| SCHEMBL9490605 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTKDM4ENPC1LMNA | |
| SCHEMBL9490706 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTKDM4ENPC1LMNA | |
| SCHEMBL9496042 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTKDM4ENPC1LMNA | |
| SCHEMBL9781759 | 0.79 | CA12 (0.69) | SMN1; SMN2MAPTCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068251-A | Nonsteroidal antiinflammatory agents, hydroxyurea derivatives | ABBOTT LABORATORIES (US) | 1991-11-26 | — | — | US | disclosed |