Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130081 | 0.92 | KMT2A (0.39) | SLC6A3KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL9131131 | 0.90 | KDM4E (0.44) | CYP2D6KMT2AMEN1CYP3A4L3MBTL1 | |
| SCHEMBL9131466 | 0.88 | ALDH1A1 (0.41) | PDPK1CYP2D6L3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL9131152 | 0.86 | TACR1 (0.36) | CYP2D6KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL9127374 | 0.84 | LMNA (0.40) | L3MBTL1SMN1; SMN2ALDH1A1LMNATBXA2R | |
| SCHEMBL9132898 | 0.82 | MAPT (0.41) | CYP2D6KMT2AMEN1L3MBTL1MAPK1 | |
| SCHEMBL9130212 | 0.82 | PDPK1 (0.40) | PDPK1TDP1CYP2D6SLC6A3KMT2A | |
| SCHEMBL9130557 | 0.82 | PDPK1 (0.40) | PDPK1TDP1CYP2D6SLC6A3KMT2A | |
| SCHEMBL9133627 | 0.80 | ALDH1A1 (0.44) | TDP1CYP2D6KMT2AMEN1CYP3A4 | |
| SCHEMBL9130770 | 0.79 | KDM4E (0.39) | KMT2AMEN1L3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472970-A | Allylaminoesters and their application in therapeutics | INSTITUT DE RECHERCHE JOUVEINAL S.A. (FR) | 1995-12-05 | — | — | US | disclosed |