Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | CYBB | P04839 | 1/20 | 0.36 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.36 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17026782 | 0.82 | KMT2A (0.37) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL9147420 | 0.81 | MAPT (0.39) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL31318554 | 0.79 | HTR2C (0.38) | KMT2AMAPTEPHX2 | |
| SCHEMBL9126810 | 0.78 | TRPV1 (0.39) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL1670891 | 0.76 | AHR (0.35) | MEN1KMT2AGAAMAPTL3MBTL1 | |
| SCHEMBL13090969 | 0.76 | HSD17B10 (0.49) | KMT2AGAAMAPTKDM4EALDH1A1 | |
| SCHEMBL8470066 | 0.71 | ACE2 (0.42) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL31751274 | 0.71 | TSHR (0.45) | GAAMAPTKDM4EALDH1A1 | |
| SCHEMBL9128758 | 0.71 | ACE2 (0.46) | MEN1KMT2AACE2CYBBNOX3 | |
| SCHEMBL31318556 | 0.71 | ALOX5 (0.40) | KMT2AGAAMAPTALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |
| US-5440036-A | For cardiovascular and respiratory system disorders | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| EP-0602458-A1 | 1,4-Benzoxazine derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |