Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | FABP6 | P51161 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR5A | P47898 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13090969 | 0.79 | HSD17B10 (0.49) | MAPTHTR5AKMT2A | |
| SCHEMBL1670891 | 0.79 | AHR (0.35) | HTR2CMAPTKMT2A | |
| SCHEMBL9130257 | 0.79 | MEN1 (0.39) | MAPTKMT2AEPHX2 | |
| SCHEMBL31751274 | 0.74 | TSHR (0.45) | HTR2CMAPTKCNH2 | |
| SCHEMBL31318556 | 0.74 | ALOX5 (0.40) | HTR2CMAPTHTR5AKMT2A | |
| SCHEMBL13209512 | 0.74 | ALOX5 (0.40) | HTR2CMAPTHTR5AKMT2A | |
| SCHEMBL23957135 | 0.71 | DRD2 (0.48) | HTR2CDRD2HTR2AEPHX2KCNH2 | |
| SCHEMBL31750428 | 0.70 | ALOX5 (0.51) | MAPTKMT2AKCNH2 | |
| SCHEMBL31318578 | 0.70 | CCNC (0.30) | — | |
| SCHEMBL21762790 | 0.70 | HTR2C (0.34) | HTR2CAKR1B1AKR1B10MAPTAKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059989-A | URAT1 inhibitor, preparation method and application thereof | 中国药科大学 | 2024-12-03 | — | — | CN | disclosed |