Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129342 | 0.82 | QDPR (0.43) | QDPRALDH1A1KMT2A | |
| SCHEMBL9644027 | 0.79 | QDPR (0.39) | QDPR | |
| SCHEMBL13783321 | 0.77 | QDPR (0.42) | QDPR | |
| SCHEMBL13599361 | 0.76 | QDPR (0.37) | QDPRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4426898 | 0.75 | HRH3 (0.38) | QDPRALDH1A1KMT2ACHRM2CHRM4 | |
| SCHEMBL6947872 | 0.74 | QDPR (0.36) | QDPR | |
| SCHEMBL3424079 | 0.74 | QDPR (0.40) | QDPR | |
| SCHEMBL10752307 | 0.74 | QDPR (0.36) | QDPRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9127424 | 0.74 | QDPR (0.36) | QDPR | |
| SCHEMBL7607024 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325263-B1 | TETRAHYDROPYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM KG (DE) | 1992-09-23 | — | — | EP | claimed |
| EP-0325263-A1 | Tetrahydropyridine derivatives | BOEHRINGER INGELHEIM KG (DE) | 1989-07-26 | — | — | EP | claimed |
| US-5422353-A | Alzheimer*s disease, glaucoma treatment | BOEHRINGER INGELHEIM KG (DE) | 1995-06-06 | — | — | US | disclosed |
| EP-0325263-B1 | TETRAHYDROPYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM KG (DE) | 1992-09-23 | — | — | EP | disclosed |
| EP-0325263-A1 | Tetrahydropyridine derivatives | BOEHRINGER INGELHEIM KG (DE) | 1989-07-26 | — | — | EP | disclosed |