Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL9129197 | 0.85 | CYP3A4 (0.37) | QDPRALDH1A1KMT2A | |
| Fumaric Acid SCHEMBL9129206 | 0.85 | CYP3A4 (0.37) | QDPRALDH1A1KMT2A | |
| SCHEMBL9129304 | 0.84 | QDPR (0.41) | QDPR | |
| SCHEMBL9130285 | 0.82 | QDPR (0.36) | QDPRALDH1A1KMT2A | |
| SCHEMBL14593825 | 0.81 | QDPR (0.39) | QDPRALDH1A1KMT2A | |
| SCHEMBL9129238 | 0.81 | QDPR (0.39) | QDPRALDH1A1KMT2A | |
| SCHEMBL9129177 | 0.80 | QDPR (0.38) | QDPRALDH1A1KMT2A | |
| SCHEMBL7607024 | 0.78 | — | — | |
| SCHEMBL13001514 | 0.77 | HRH3 (0.46) | — | |
| SCHEMBL9127898 | 0.77 | ADRA2A (0.38) | QDPRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1224361-A | — | — | None | — | — | JP | disclosed |
| WO-2024105553-A1 | BICYCLIC HETEROCYCLES AND THEIR USE AS WRN INHIBITORS | NOVARTIS AG (CH) | 2024-05-23 | — | — | WO | disclosed |
| US-5422353-A | Alzheimer*s disease, glaucoma treatment | BOEHRINGER INGELHEIM KG (DE) | 1995-06-06 | — | — | US | disclosed |
| EP-0325263-B1 | TETRAHYDROPYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM KG (DE) | 1992-09-23 | — | — | EP | disclosed |
| JP-H01224361-A | TETRAHYDROPYRIDINE DERIVATIVE AND ITS PREPARATION | BOEHRINGER INGELHEIM KG | 1989-09-07 | — | — | JP | disclosed |
| EP-0325263-A1 | Tetrahydropyridine derivatives | BOEHRINGER INGELHEIM KG (DE) | 1989-07-26 | — | — | EP | disclosed |