Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852967 | 0.81 | MTNR1A (0.57) | SMN1; SMN2HTTCYP2D6ALDH1A1ACP3 | |
| SCHEMBL5312101 | 0.80 | TSHR (0.50) | SMN1; SMN2HTTL3MBTL1TSHRCYP2D6 | |
| SCHEMBL4879511 | 0.75 | POLB (0.58) | TSHRCYP2D6CYP2C9CYP2C19CYP1A2 | |
| Formamide SCHEMBL8868988 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTL3MBTL1OPRM1OPRK1 | |
| SCHEMBL7006614 | 0.74 | TSHR (0.53) | SMN1; SMN2HTTL3MBTL1TSHRCYP2D6 | |
| Ammonia Solution, Strong SCHEMBL8867125 | 0.73 | CYP2D6 (0.52) | SMN1; SMN2HTTL3MBTL1OPRM1OPRK1 | |
| SCHEMBL13801233 | 0.73 | TSHR (0.54) | SMN1; SMN2L3MBTL1TSHRALDH1A1POLB | |
| SCHEMBL11509158 | 0.72 | KMT2A (0.58) | SMN1; SMN2OPRM1OPRK1TSHRCYP2D6 | |
| SCHEMBL30482083 | 0.70 | TSHR (0.59) | SMN1; SMN2TSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL1039984 | 0.70 | TSHR (0.59) | SMN1; SMN2TSHRCYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430044-A | Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties | FISONS CORPORATION (GB) | 1995-07-04 | — | — | US | disclosed |
| US-5331007-A | Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties | FISONS CORPORATION (US) | 1994-07-19 | — | — | US | disclosed |