Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | ADH1B | P00325 | 1/20 | 0.50 |
| ▸ | ADH1C | P00326 | 1/20 | 0.50 |
| ▸ | ADH1A | P07327 | 1/20 | 0.50 |
| ▸ | ADH7 | P40394 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183916 | 0.83 | EPHX1 (0.47) | MTNR1AMTNR1BEPHX1ADH1BADH1C | |
| SCHEMBL9130338 | 0.81 | SMN1; SMN2 (0.47) | CYP2D6ACP3ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5142175 | 0.80 | KDM4E (0.42) | MTNR1AMTNR1BEPHX1ADH1BADH1C | |
| SCHEMBL16973460 | 0.79 | MTNR1A (0.46) | MTNR1AMTNR1BCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL3961978 | 0.77 | KMT2A (0.42) | MTNR1AMTNR1BADH1BADH1CADH1A | |
| SCHEMBL11775077 | 0.77 | CYP2C19 (0.46) | MTNR1AMTNR1BEPHX1ADH1BADH1C | |
| SCHEMBL1549013 | 0.77 | GRIN1 (0.50) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL7430250 | 0.76 | EPHX1 (0.57) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL5252227 | 0.76 | TAAR1 (0.58) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL146771 | 0.76 | MTNR1A (0.55) | MTNR1AMTNR1BEPHX1TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441226-A1 | (cyanomethyl)pyridines useful as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1991-08-14 | — | — | EP | disclosed |