Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 6/20 | 0.41 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.41 |
| ▸ | RXRB | P28702 | 7/20 | 0.41 |
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | RARG | P13631 | 4/20 | 0.40 |
| ▸ | RXRG | P48443 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131231 | 0.85 | RXRA (0.50) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL7897312 | 0.69 | RXRA (0.53) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL11077426 | 0.68 | MEN1 (0.42) | RXRACYP26A1RXRBRARBRARG | |
| SCHEMBL8707418 | 0.67 | RXRA (0.72) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL7889505 | 0.67 | RXRA (0.60) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL5204065 | 0.66 | KMT2A (0.36) | — | |
| SCHEMBL2788640 | 0.65 | CYP3A4 (0.70) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL20398882 | 0.65 | RXRA (0.54) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL8708782 | 0.64 | RXRA (0.74) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL7756598 | 0.64 | RXRA (0.64) | RXRACYP26B1CYP26A1RXRBRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428052-A | Classifiable as retinoids; skin disorders, corneopathy | CENTRE INTERNATIONALE DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1995-06-27 | — | — | US | disclosed |
| US-5288744-A | Tetramethyltetrahydronaphthyl benzothiazole for treating skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1994-02-22 | — | — | US | disclosed |
| US-5260295-A | Retinoic acid derivatives, cosmetics, skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1993-11-09 | — | — | US | disclosed |
| US-5059621-A | Treatment of dermatologic ailments linked to keratinization disorder | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1991-10-22 | — | — | US | disclosed |
| US-4920140-A | Skin disorders | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1990-04-24 | — | — | US | disclosed |
| US-4740519-A | Benzo (b) thiophene carboxylate derivatives and pharmaceutical compositions | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1988-04-26 | — | — | US | disclosed |