Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 14/20 | 0.64 |
| ▸ | CYP26B1 | Q9NR63 | 6/20 | 0.53 |
| ▸ | CYP26A1 | O43174 | 6/20 | 0.53 |
| ▸ | RXRB | P28702 | 8/20 | 0.49 |
| ▸ | RARB | P10826 | 6/20 | 0.48 |
| ▸ | RARG | P13631 | 6/20 | 0.48 |
| ▸ | RXRG | P48443 | 5/20 | 0.47 |
| ▸ | RARA | P10276 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7897312 | 0.85 | RXRA (0.53) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL2433471 | 0.82 | RXRA (0.67) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL7752831 | 0.81 | RXRA (0.68) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL8333684 | 0.81 | RXRA (0.61) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL20414587 | 0.80 | RXRA (0.67) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL7760432 | 0.79 | RXRA (0.69) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL30012842 | 0.78 | RXRA (1.00) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL3453249 | 0.78 | RXRA (1.00) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL7760265 | 0.78 | RXRA (0.54) | RXRACYP26B1CYP26A1RXRBRARB | |
| SCHEMBL7761565 | 0.78 | CYP26B1 (0.58) | RXRACYP26B1CYP26A1RXRBRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915823-B1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CT INTERNAT DE (FR) | 2001-04-18 | — | — | EP | disclosed |
| EP-0915823-A1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998022423-A1 | BI-AROMATIC COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME AND USES | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1998-05-28 | — | — | WO | disclosed |