Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | BRCA1 | P38398 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.54 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340741 | 0.91 | HPGD (0.63) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL10435860 | 0.90 | HPGD (0.62) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL2322100 | 0.82 | HPGD (0.54) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL293820 | 0.80 | FTO (0.59) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL1908131 | 0.80 | HPGD (0.63) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL9056795 | 0.80 | HPGD (0.51) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL7527626 | 0.79 | FTO (0.58) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL7517672 | 0.79 | FTO (0.58) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL498269 | 0.79 | FTO (0.58) | HPGDALDH1A1BRCA1HSD17B10ALOX12 | |
| SCHEMBL27664913 | 0.79 | FTO (0.58) | HPGDALDH1A1BRCA1HSD17B10ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5421897-A | Applying liquid composition to surface contaminated with lead, solidifying into matrix which sequesters lead, removing matrix | GRAWE JOHN (US) | 1995-06-06 | — | — | US | claimed |
| US-5421897-A | Applying liquid composition to surface contaminated with lead, solidifying into matrix which sequesters lead, removing matrix | GRAWE JOHN (US) | 1995-06-06 | — | — | US | disclosed |