SCHEMBL498269

SCHEMBL498269

O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2cc(Br)c(Br)c(Br)c21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.58
HPGD P15428 3/20 0.58
MAPT P10636 3/20 0.58
PRMT1 Q99873 2/20 0.58
RECQL P46063 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
MEN1 O00255 2/20 0.58
HTT P42858 2/20 0.58
KMT2A Q03164 2/20 0.58
CYP2C19 P33261 1/20 0.58
BLM P54132 1/20 0.58
SMAD3 P84022 1/20 0.58
ACE2 Q9BYF1 1/20 0.58
ALDH1A1 P00352 3/20 0.55
BRCA1 P38398 2/20 0.55
HSD17B10 Q99714 2/20 0.55
ALOX12 P18054 2/20 0.55
CYP2C9 P11712 1/20 0.55
ALOX15 P16050 1/20 0.55
CYP3A4 P08684 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27664913 0.90 FTO (0.58) FTOHPGDMAPTPRMT1RECQL
SCHEMBL293820 0.88 FTO (0.59) FTOHPGDMAPTPRMT1RECQL
SCHEMBL7527626 0.87 FTO (0.58) FTOHPGDMAPTPRMT1RECQL
SCHEMBL7517672 0.87 FTO (0.58) FTOHPGDMAPTPRMT1RECQL
SCHEMBL10900247 0.87 FTO (0.52) FTOHPGDMAPTPRMT1RECQL
SCHEMBL6580619 0.84 HPGD (0.58) FTOHPGDMAPTPRMT1RECQL
SCHEMBL340741 0.83 HPGD (0.63) FTOHPGDMAPTPRMT1RECQL
SCHEMBL1908131 0.83 HPGD (0.63) FTOHPGDMAPTPRMT1RECQL
SCHEMBL10435860 0.82 HPGD (0.62) FTOHPGDMAPTPRMT1RECQL
SCHEMBL9130573 0.79 HPGD (0.62) FTOHPGDMAPTPRMT1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023192788-A1 DEVELOPER COMPOSITION COMPRISING DIRECT DYE L'OREAL (FR) 2023-10-05 WO claimed
US-20230310285-A1 DEVELOPER COMPOSITION COMPRISING DIRECT DYE L'OREAL (FR) 2023-10-05 US claimed
US-11561155-B2 Heavy metal ion-hematein-complexes useful as ex vivo contrast agent for a computed tomography scanning of a biological sample, ex vivo method for investigating a biological sample, and use of the complexes Technische Universität München (DE) 2023-01-24 US claimed
US-20210371436-A1 NOVEL HEAVY METAL ION-LIGAND-COMPLEXES USEFUL AS EX VIVO CONTRAST AGENT FOR A COMPUTED TOMOGRAPHY SCANNING OF A BIOLOGICAL SAMPLE, EX VIVO METHOD FOR INVESTIGATING A BIOLOGICAL SAMPLE, AND USE OF THE COMPLEXES Technische Universität München (DE) 2021-12-02 US claimed
US-20200271554-A1 NOVEL HEAVY METAL ION-HEMATEIN-COMPLEXES USEFUL AS EX VIVO CONTRAST AGENT FOR A COMPUTED TOMOGRAPHY SCANNING OF A BIOLOGICAL SAMPLE, EX VIVO METHOD FOR INVESTIGATING A BIOLOGICAL SAMPLE, AND USE OF THE COMPLEXES Technische Universität München (DE) 2020-08-27 US claimed
EP-3694844-A1 NOVEL HEAVY METAL ION-HEMATEIN-COMPLEXES USEFUL AS EX VIVO CONTRAST AGENT FOR A COMPUTED TOMOGRAPHY SCANNING OF A BIOLOGICAL SAMPLE, EX VIVO METHOD FOR INVESTIGATING A BIOLOGICAL SAMPLE, AND USE OF THE COMPLEXES Technische Universität München (DE) 2020-08-19 EP claimed
EP-3694845-A1 NOVEL HEAVY METAL ION-LIGAND-COMPLEXES USEFUL AS EX VIVO CONTRAST AGENT FOR A COMPUTED TOMOGRAPHY SCANNING OF A BIOLOGICAL SAMPLE, EX VIVO METHOD FOR INVESTIGATING A BIOLOGICAL SAMPLE, AND USE OF THE COMPLEXES Technische Universität München (DE) 2020-08-19 EP claimed
WO-2019073065-A1 NOVEL HEAVY METAL ION-LIGAND-COMPLEXES USEFUL AS EX VIVO CONTRAST AGENT FOR A COMPUTED TOMOGRAPHY SCANNING OF A BIOLOGICAL SAMPLE, EX VIVO METHOD FOR INVESTIGATING A BIOLOGICAL SAMPLE, AND USE OF THE COMPLEXES Technische Universität München (DE) 2019-04-18 WO claimed
WO-2019073064-A1 NOVEL HEAVY METAL ION-HEMATEIN-COMPLEXES USEFUL AS EX VIVO CONTRAST AGENT FOR A COMPUTED TOMOGRAPHY SCANNING OF A BIOLOGICAL SAMPLE, EX VIVO METHOD FOR INVESTIGATING A BIOLOGICAL SAMPLE, AND USE OF THE COMPLEXES Technische Universität München (DE) 2019-04-18 WO claimed
CN-118215417-A Antibacterial multi-layer fabric medium and preparation method thereof 乔治华盛顿大学 2024-06-18 CN disclosed
WO-2024124139-A1 METHODS AND DEVICES FOR MULTIPHOTON IMAGING AND LASER-TISSUE INTERACTIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-13 WO disclosed
US-11975221-B2 Anti-microbial multilayer fabric media and method for making same Shuai Danmeng (US) 2024-05-07 US disclosed
US-20240041739-A1 BIOPHOTONIC COMPOSITIONS AND METHODS FOR PROVIDING BIOPHOTONIC TREATMENT KLOX TECHNOLOGIES INC. (CA) 2024-02-08 US disclosed
EP-4274443-A1 ANTI-MICROBIAL MULTILAYER FABRIC MEDIA AND METHOD FOR MAKING SAME Shuai, Danmeng (US) 2023-11-15 EP disclosed
US-4615878-A Metachromatic dye sorption means for differential determination of sub-populations of lymphocytes CYTOCOLOR INC., A CORP OF OH 1986-10-07 US disclosed
EP-0179107-A1 METACHROMATIC DYE SORPTION MEANS FOR DIFFERENTIAL DETERMINATION OF SUB-POPULATIONS OF LYMPHOCYTES. KASS LAWRENCE 1986-04-30 EP disclosed
US-4581223-A STAINS FOR BLOOD COUNTS CYTOCOLOR INC., A CORP OF OH 1986-04-08 US disclosed
WO-1985005179-A1 METACHROMATIC DYE SORPTION MEANS FOR DIFFERENTIAL DETERMINATION OF SUB-POPULATIONS OF LYMPHOCYTES MERCK PATENT GMBH (DE) 1985-11-21 WO disclosed
US-4500509-A Metachromatic dye sorption and fluorescent light emmisive means for differential determination of developmental stages of neutrophilic granulocytic cells and other leukocytes CYTOCOLOR INC., A CORP OF OH 1985-02-19 US disclosed
US-4400370-A Metachromatic dye sorption means for differential determination of leukocytes CYTOCOLOR INC., A CORP OF OH 1983-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210371436-A1 NOVEL HEAVY METAL ION-LIGAND-COMPLEXES USEFUL AS EX VIVO CONTRAST AGENT FOR A COMPUTED TOMOGRAPHY SCANNING OF A BIOLOGICAL SAMPLE, EX VIVO METHOD FOR INVESTIGATING A BIOLOGICAL SAMPLE, AND USE OF THE COMPLEXES EDNRB, ELANE, CD68 FTO 3678/4885HPGD 3834/4885MAPT 3170/4885
US-11561155-B2 Heavy metal ion-hematein-complexes useful as ex vivo contrast agent for a computed tomography scanning of a biological sample, ex vivo method for investigating a biological sample, and use of the complexes SERPINC1, CD63, CD68 FTO 4588/4885HPGD 3139/4885MAPT 3682/4885
US-20200271554-A1 NOVEL HEAVY METAL ION-HEMATEIN-COMPLEXES USEFUL AS EX VIVO CONTRAST AGENT FOR A COMPUTED TOMOGRAPHY SCANNING OF A BIOLOGICAL SAMPLE, EX VIVO METHOD FOR INVESTIGATING A BIOLOGICAL SAMPLE, AND USE OF THE COMPLEXES SERPINC1, CD63, CD68 FTO 4620/4885HPGD 3314/4885MAPT 3711/4885
US-20230310285-A1 DEVELOPER COMPOSITION COMPRISING DIRECT DYE TYR, CYB5R3, POLR1C FTO 39/4885HPGD 506/4885MAPT 3307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.