Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | GPR183 | P32249 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127371 | 0.93 | TBXA2R (0.39) | MMP1LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9132894 | 0.84 | TSHR (0.36) | ALDH1A1MAPTHTT | |
| SCHEMBL9130770 | 0.83 | KDM4E (0.39) | MMP1GPR183KDM4ELMNAALDH1A1 | |
| SCHEMBL9131147 | 0.83 | TSHR (0.36) | LMNASMN1; SMN2 | |
| SCHEMBL9130072 | 0.80 | LMNA (0.37) | LMNASMN1; SMN2HPGDGAAMAOA | |
| SCHEMBL9130557 | 0.79 | PDPK1 (0.40) | LMNAALDH1A1MAPTHTTRAB9A | |
| SCHEMBL9130212 | 0.79 | PDPK1 (0.40) | LMNAALDH1A1MAPTHTTRAB9A | |
| SCHEMBL9131463 | 0.78 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2TBXA2RPTGER1PTGER4 | |
| SCHEMBL9133623 | 0.77 | ALDH1A1 (0.38) | KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9131126 | 0.77 | KDM4E (0.39) | KDM4ELMNAALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472970-A | Allylaminoesters and their application in therapeutics | INSTITUT DE RECHERCHE JOUVEINAL S.A. (FR) | 1995-12-05 | — | — | US | disclosed |