Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | KLK7 | P49862 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907816 | 1.00 | HPGD (0.53) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL697221 | 0.98 | ALDH1A1 (0.50) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL697966 | 0.94 | TSHR (0.50) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL698490 | 0.89 | — | — | |
| SCHEMBL560936 | 0.88 | EPHX2 (0.53) | HPGDALDH1A1EPHX2TSHR | |
| Hydrochloric Acid SCHEMBL14167163 | 0.87 | TSHR (0.52) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL27672250 | 0.86 | EPHX2 (0.53) | HPGDALDH1A1KMT2AEPHX2TSHR | |
| SCHEMBL28208913 | 0.86 | ALDH1A1 (0.49) | HPGDALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8885696 | 0.86 | TSHR (0.54) | HPGDALDH1A1EPHX2TSHR | |
| SCHEMBL10977640 | 0.85 | EPHX2 (0.55) | ALDH1A1KMT2AEPHX2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468774-A | Antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |
| US-5420153-A | Antiinflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-05-30 | — | — | US | disclosed |
| US-5366993-A | Antiinflammatory, antifertility | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-11-22 | — | — | US | disclosed |
| WO-1993022305-A1 | TETRONIC, THIOTETRONIC AND TETRAMIC ACID DERIVATIVES AS PHOSPHOLIPASE A2 INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-11-11 | — | — | WO | disclosed |