⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847169 | 0.79 | ALOX5 (0.53) | — | |
| SCHEMBL173833 | 0.77 | — | — | |
| SCHEMBL10706563 | 0.77 | — | — | |
| SCHEMBL3264866 | 0.77 | — | — | |
| SCHEMBL11875926 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL11598999 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL9697890 | 0.75 | — | — | |
| SCHEMBL9471474 | 0.75 | — | — | |
| SCHEMBL11665140 | 0.75 | — | — | |
| Silver SCHEMBL11396170 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395931-A | 6-amido-1-methyl-2-(substituted-thio)carbapenems | MERCK & CO., INC. (US) | 1995-03-07 | — | — | US | disclosed |
| EP-0350210-A2 | Novel 6-amido-1-methyl-2-(substituted-thio)-carbapenems | MERCK & CO. INC. (US) | 1990-01-10 | — | — | EP | disclosed |