Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 19/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129888 | 0.89 | OPRK1 (0.46) | OPRK1KCNH2 | |
| SCHEMBL9129660 | 0.86 | OPRK1 (0.48) | OPRK1 | |
| SCHEMBL9129777 | 0.82 | OPRK1 (0.45) | OPRK1 | |
| SCHEMBL9127858 | 0.82 | OPRK1 (0.53) | OPRK1 | |
| SCHEMBL9128047 | 0.80 | PARP1 (0.47) | OPRK1 | |
| SCHEMBL9130908 | 0.74 | OPRK1 (0.48) | OPRK1KCNH2 | |
| SCHEMBL16413116 | 0.72 | OPRK1 (0.43) | OPRK1KCNH2MCHR2MCHR1 | |
| SCHEMBL16413111 | 0.72 | OPRK1 (0.43) | OPRK1KCNH2MCHR2MCHR1 | |
| SCHEMBL20554842 | 0.72 | OPRK1 (0.43) | OPRK1KCNH2MCHR2MCHR1 | |
| SCHEMBL9128883 | 0.71 | OPRK1 (0.60) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670318-A2 | Acetamides with analgesic and neuroprotective activity | MERCK PATENT GmbH (DE) | 1995-09-06 | — | — | EP | claimed |
| US-5472961-A | Acetamides | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-12-05 | — | — | US | disclosed |
| EP-0670318-A2 | Acetamides with analgesic and neuroprotective activity | MERCK PATENT GmbH (DE) | 1995-09-06 | — | — | EP | disclosed |