Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130914 | 1.00 | MEN1 (0.39) | MEN1KMT2AMAPK1SMN1; SMN2PDPK1 | |
| SCHEMBL9130189 | 0.88 | ALDH1A1 (0.44) | KMT2ASMN1; SMN2CYP2D6CYP3A4L3MBTL1 | |
| SCHEMBL9130195 | 0.88 | ALDH1A1 (0.44) | KMT2ASMN1; SMN2CYP2D6CYP3A4L3MBTL1 | |
| SCHEMBL9129216 | 0.86 | TSHR (0.39) | MEN1KMT2AMAPK1SMN1; SMN2CYP3A4 | |
| SCHEMBL9129210 | 0.86 | TSHR (0.39) | MEN1KMT2AMAPK1SMN1; SMN2CYP3A4 | |
| SCHEMBL9130916 | 0.81 | TDP1 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2PDPK1 | |
| SCHEMBL9130212 | 0.78 | PDPK1 (0.40) | MEN1KMT2AMAPK1SMN1; SMN2PDPK1 | |
| SCHEMBL9130557 | 0.78 | PDPK1 (0.40) | MEN1KMT2AMAPK1SMN1; SMN2PDPK1 | |
| SCHEMBL9130200 | 0.71 | ALDH1A1 (0.48) | MEN1KMT2ATDP1CYP2D6CYP3A4 | |
| SCHEMBL9129221 | 0.70 | MEN1 (0.40) | MEN1KMT2AMAPK1SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472970-A | Allylaminoesters and their application in therapeutics | INSTITUT DE RECHERCHE JOUVEINAL S.A. (FR) | 1995-12-05 | — | — | US | disclosed |