Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130916 | 0.86 | TDP1 (0.45) | MEN1KMT2ASMN1; SMN2MAPK1TSHR | |
| SCHEMBL9133069 | 0.81 | FDPS (0.39) | MEN1KMT2ASMN1; SMN2TSHRFDPS | |
| SCHEMBL9133067 | 0.81 | FDPS (0.39) | MEN1KMT2ASMN1; SMN2TSHRFDPS | |
| SCHEMBL9129255 | 0.81 | FDPS (0.39) | MEN1KMT2ASMN1; SMN2TSHRFDPS | |
| SCHEMBL9130200 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2AHPGDCYP3A4CYP2C19 | |
| SCHEMBL9129216 | 0.79 | TSHR (0.39) | MEN1KMT2ASMN1; SMN2MAPK1TACR1 | |
| SCHEMBL9129210 | 0.79 | TSHR (0.39) | MEN1KMT2ASMN1; SMN2MAPK1TACR1 | |
| SCHEMBL9131152 | 0.76 | TACR1 (0.36) | MEN1KMT2ASMN1; SMN2MAPK1TACR1 | |
| Hydrochloric Acid SCHEMBL27753528 | 0.74 | FDPS (0.39) | MEN1KMT2ASMN1; SMN2TSHRFDPS | |
| SCHEMBL9130906 | 0.70 | MEN1 (0.39) | MEN1KMT2ASMN1; SMN2MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472970-A | Allylaminoesters and their application in therapeutics | INSTITUT DE RECHERCHE JOUVEINAL S.A. (FR) | 1995-12-05 | — | — | US | disclosed |