Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | DHPS | P49366 | 2/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132797 | 0.92 | RXFP1 (0.58) | NR4A2RXFP1KMT2AMEN1NPC1 | |
| SCHEMBL9131833 | 0.89 | KMT2A (0.47) | NR4A2RXFP1KMT2AMEN1NPC1 | |
| SCHEMBL9129235 | 0.86 | MEN1 (0.50) | KMT2AMEN1NPC1DHPSHSD17B10 | |
| SCHEMBL9795045 | 0.86 | HDAC1 (0.50) | KMT2AMEN1NPC1DHPSHSD17B10 | |
| SCHEMBL9132310 | 0.86 | MEN1 (0.50) | KMT2AMEN1NPC1DHPSHSD17B10 | |
| SCHEMBL9795192 | 0.85 | HSD17B10 (0.60) | RXFP1KMT2AMEN1NPC1DHPS | |
| SCHEMBL9131919 | 0.85 | MEN1 (0.49) | KMT2AMEN1NPC1DHPSHSD17B10 | |
| SCHEMBL9795043 | 0.85 | HDAC1 (0.52) | KMT2AMEN1NPC1DHPSHSD17B10 | |
| SCHEMBL9132823 | 0.83 | DHPS (0.50) | RXFP1KMT2AMEN1NPC1DHPS | |
| Hydrochloric Acid SCHEMBL9132778 | 0.82 | DHPS (0.49) | RXFP1KMT2AMEN1NPC1DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380722-A | Antiarrhythmia agents | ROUSSEL-UCLAF (FR) | 1995-01-10 | — | — | US | disclosed |
| US-5084455-A | Antiarrhythmia agents for mammals | ROUSSEL UCLAF (FR) | 1992-01-28 | — | — | US | disclosed |
| US-4908367-A | Antiarrythmic agents | Uclaf, Roussel (FR) | 1990-03-13 | — | — | US | disclosed |
| US-4791109-A | Novel indole carboxamides | ROUSSEL UCLAF (FR) | 1988-12-13 | — | — | US | disclosed |