SCHEMBL9131704

SCHEMBL9131704

C#CCc1cc(Cc2ccccc2)cc(C(C)(C)C)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSPA5 P11021 2/20 0.48
▸ GAA P10253 2/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ PTPN1 P18031 2/20 0.41
▸ PTPN2 P17706 1/20 0.41
▸ PTPN6 P29350 1/20 0.41
▸ BCL2 P10415 1/20 0.40
▸ BCL2L1 Q07817 1/20 0.40
▸ CYP2C9 P11712 4/20 0.39
▸ CYP2C19 P33261 4/20 0.39
▸ HIF1A Q16665 3/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ TSHR P16473 3/20 0.38
▸ CYP1A2 P05177 2/20 0.38
▸ CYP3A4 P08684 2/20 0.38
▸ DHFR P00374 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ LMNA P02545 2/20 0.36
▸ CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12430324 0.85 HSPA5 (0.65) HSPA5GAAMEN1KMT2APTPN1
SCHEMBL9817016 0.85 HSPA5 (0.60) HSPA5GAAMEN1KMT2APTPN1
SCHEMBL1187217 0.82 MEN1 (0.57) HSPA5GAAMEN1KMT2APTPN1
SCHEMBL11352569 0.77 HSPA5 (0.76) HSPA5GAAMEN1KMT2APTPN1
SCHEMBL5009340 0.76 CYP2C9 (0.50) HSPA5GAAMEN1KMT2APTPN1
SCHEMBL4565241 0.76 HSPA5 (0.64) HSPA5GAAMEN1KMT2APTPN1
SCHEMBL28117868 0.75 ALDH1A1 (0.51) HSPA5GAAMEN1KMT2APTPN1
Hypophosphorous Acid SCHEMBL6556020 0.75 GAA (0.54) HSPA5GAAMEN1KMT2APTPN1
Benzene SCHEMBL9807217 0.75 ALDH1A1 (0.59) HSPA5GAAMEN1KMT2ACYP2C9
Phenol SCHEMBL20657088 0.74 MEN1 (0.55) HSPA5GAAMEN1KMT2ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 — — EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 — — EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 — — US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 — — US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 — — US disclosed
US-5021321-A Photothermography; antifogging agents; contrast; lamination of matrix of silver salts and reducing agent and dispersed particles of dye, polymer precursor and photoinitiator CANON KABUSHIKI KAISHA (JP) 1991-06-04 — — US disclosed
EP-0412851-A2 Photosensitive member and multi-color image forming method CANON KABUSHIKI KAISHA (JP) 1991-02-13 — — EP disclosed
EP-0363790-A2 Image forming method and image forming medium CANON KABUSHIKI KAISHA (JP) 1990-04-18 — — EP disclosed
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