Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128773 | 1.00 | ALOX5 (0.46) | ALOX5BACE1DPP4HDAC3HDAC4 | |
| SCHEMBL9128782 | 1.00 | ALOX5 (0.46) | ALOX5BACE1DPP4HDAC3HDAC4 | |
| SCHEMBL9380927 | 0.85 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9128036 | 0.80 | ALOX5 (0.39) | ALOX5DPP4 | |
| SCHEMBL9128046 | 0.80 | ALOX5 (0.39) | ALOX5DPP4 | |
| SCHEMBL9128042 | 0.80 | ALOX5 (0.39) | ALOX5DPP4 | |
| SCHEMBL9125728 | 0.80 | ALOX5 (0.33) | ALOX5DPP4PGR | |
| SCHEMBL9125743 | 0.80 | ALOX5 (0.33) | ALOX5DPP4PGR | |
| SCHEMBL9131746 | 0.80 | ALOX5 (0.33) | ALOX5DPP4PGR | |
| SCHEMBL9128144 | 0.79 | ALOX5 (0.48) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407959-A | Antiallergens, antiinflammatory agents | ABBOTT LABORATORIES (US) | 1995-04-18 | — | — | US | disclosed |