SCHEMBL9133282

SCHEMBL9133282

CCC1OC1c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.43
CHRNA7 P36544 1/20 0.40
MDM2 Q00987 3/20 0.37
SLC6A3 Q01959 2/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
DRD2 P14416 1/20 0.37
KDM1A O60341 1/20 0.37
RCOR1 Q9UKL0 1/20 0.37
RAB9A P51151 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
L3MBTL4 Q8NA19 1/20 0.34
LMNA P02545 2/20 0.33
CYP2A6 P11509 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
ALOX12 P18054 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9132881 0.81 SLC5A2 (0.36) LMNAALDH1A1ALOX12SMN1; SMN2
SCHEMBL10464525 0.81 SLC6A2 (0.38) FTOCHRNA7MDM2SLC6A3SLC6A2
SCHEMBL50998 0.80 TSHR (0.43) KDM1ALMNASMN1; SMN2
SCHEMBL7951294 0.80 TSHR (0.43) KDM1ALMNASMN1; SMN2
SCHEMBL4079821 0.79 PTGS2 (0.41) FTOSLC6A3SLC6A2SLC6A4RET
SCHEMBL8481899 0.79 PTGS2 (0.41) FTOSLC6A3SLC6A2SLC6A4RET
SCHEMBL8114308 0.79 PTGS2 (0.41) FTOSLC6A3SLC6A2SLC6A4RET
SCHEMBL9132397 0.79 TP53 (0.41) KDM1ACYP2A6KDM4EALDH1A1MAPT
SCHEMBL9131857 0.79 KDM1A (0.44) MDM2SLC6A3SLC6A2SLC6A4KDM1A
SCHEMBL11958019 0.79 FTO (0.37) FTOCHRNA7MDM2SLC6A3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5466838-A Catalytic reaction of olefin with oxygen in the presence of aldehyde SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-11-14 US disclosed
EP-0540009-B1 Process for producing epoxides SUMITOMO CHEMICAL CO (JP) 1995-08-30 EP disclosed
US-5367087-A Process for producing epoxide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-22 US disclosed
EP-0540009-A1 Process for producing epoxides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-05 EP disclosed