Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CCR4 | P51679 | 1/20 | 0.45 |
| ▸ | DHPS | P49366 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL9242142 | 0.86 | MAPK1 (0.48) | MAPK1CCR4DHPSHTR6CDC25B | |
| SCHEMBL10647322 | 0.82 | DHPS (0.48) | MAPK1CCR4DHPSEGFRPDGFRB | |
| SCHEMBL27463226 | 0.79 | MEN1 (0.59) | MAPK1CCR4DHPSAHRHTR6 | |
| SCHEMBL9132873 | 0.78 | MAPK1 (0.51) | MAPK1CCR4DHPSAHRHTR6 | |
| SCHEMBL9232128 | 0.77 | AHR (0.56) | MAPK1AHRHTR6KDM4EALDH1A1 | |
| SCHEMBL29363007 | 0.77 | AHR (0.56) | MAPK1AHRHTR6KDM4EALDH1A1 | |
| SCHEMBL26495 | 0.77 | AHR (0.56) | MAPK1AHRHTR6KDM4EALDH1A1 | |
| SCHEMBL2986147 | 0.76 | MAPK14 (0.57) | MAPK1CCR4EGFRPDGFRBKDR | |
| SCHEMBL21925739 | 0.76 | MAPK1 (0.49) | MAPK1CCR4DHPSAHRHTR6 | |
| SCHEMBL12650796 | 0.76 | ROCK1 (0.49) | FLT3MKNK1MKNK2KDRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380722-A | Antiarrhythmia agents | ROUSSEL-UCLAF (FR) | 1995-01-10 | — | — | US | disclosed |
| US-4791109-A | Novel indole carboxamides | ROUSSEL UCLAF (FR) | 1988-12-13 | — | — | US | disclosed |