Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.70 |
| ▸ | FBP1 | P09467 | 2/20 | 0.66 |
| ▸ | MAOB | P27338 | 5/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.60 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134846 | 1.00 | TDP1 (0.78) | TDP1SRD5A2FBP1MAOBBCHE | |
| SCHEMBL6304378 | 0.89 | TDP1 (0.78) | TDP1SRD5A2FBP1MAOBBCHE | |
| SCHEMBL9136940 | 0.89 | MAOB (0.80) | TDP1SRD5A2MAOBBCHECYP1B1 | |
| SCHEMBL9136943 | 0.89 | MAOB (0.80) | TDP1SRD5A2MAOBBCHECYP1B1 | |
| Terephthalic Acid SCHEMBL28023943 | 0.88 | TDP1 (1.00) | TDP1SRD5A2MEN1KMT2ACES1 | |
| 4-Nitrobenzoic Acid SCHEMBL43476 | 0.88 | TDP1 (1.00) | TDP1SRD5A2MEN1KMT2ACES1 | |
| 4-Nitrobenzoic Acid SCHEMBL11331124 | 0.86 | TDP1 (0.95) | TDP1SRD5A2MEN1KMT2ACES1 | |
| 4-Nitrobenzoic Acid SCHEMBL1566327 | 0.86 | TDP1 (0.95) | TDP1SRD5A2MEN1KMT2ACES1 | |
| 4-Nitrobenzoic Acid SCHEMBL17332065 | 0.86 | TDP1 (0.95) | TDP1SRD5A2MEN1KMT2ACES1 | |
| 4-Nitrobenzoic Acid SCHEMBL7553997 | 0.86 | TDP1 (0.95) | TDP1SRD5A2MEN1KMT2ACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5412044-A | Nitro group terminated mesogenic epoxy resin adducts | THE DOW CHEMICAL COMPANY (US) | 1995-05-02 | — | — | US | claimed |
| CN-114384756-A | Resin composition, toner for developing electrostatic image, image forming method, photosensitive adhesive, and photoswitch material | 柯尼卡美能达株式会社 | 2022-04-22 | — | — | CN | disclosed |
| US-20220119424-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITechGroup MDX, LLC (US) | 2022-04-21 | — | — | US | disclosed |
| US-11242554-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | ELITECHGROUP, INC. (US) | 2022-02-08 | — | — | US | disclosed |
| US-11242554-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | ELITECHGROUP, INC. (US) | 2022-02-08 | — | — | US | disclosed |
| US-20200299755-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP, INC. (US) | 2020-09-24 | — | — | US | disclosed |
| US-20200299755-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP, INC. (US) | 2020-09-24 | — | — | US | disclosed |
| US-10738346-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | ELITECHGROUP, INC. (US) | 2020-08-11 | — | — | US | disclosed |
| US-10738346-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | ELITECHGROUP, INC. (US) | 2020-08-11 | — | — | US | disclosed |
| US-20180258471-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | ELITECHGROUP B.V. (NL) | 2018-09-13 | — | — | US | disclosed |
| US-5464912-A | Adduct with rodlike mesogenic moiety, adduct made by reacting polyepoxide with nitro/so/ compound having epoxy-reactive hydrogen; conversion of hydroxyl product to ether, ester, halide, urethane, ketone, alkane; reducing nitro/so/ to amine | THE DOW CHEMICAL COMPANY (US) | 1995-11-07 | — | — | US | disclosed |
| US-5412044-A | Nitro group terminated mesogenic epoxy resin adducts | THE DOW CHEMICAL COMPANY (US) | 1995-05-02 | — | — | US | disclosed |
| US-5344898-A | Curable composition with stilbene groups and molecular orientation | THE DOW CHEMICAL COMPANY (US) | 1994-09-06 | — | — | US | disclosed |
| US-5298575-A | Consists of at least one compound having more than one vicinal epoxide group and at least one amine terminated adduct containing one or more mesogenic moities | THE DOW CHEMICAL COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| US-4261855-A | OPTICAL BRIGHTENERS, FLUORESCENT DYES | CIBA-GEIGY CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119424-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | DNTT, NME2, DUT | TDP1 204/4885SRD5A2 1419/4885FBP1 2022/4885 |
| US-20200299755-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | DNTT, NME2, DUT | TDP1 204/4885SRD5A2 1419/4885FBP1 2022/4885 |
| US-10738346-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | DNTT, NME2, DUT | TDP1 204/4885SRD5A2 1419/4885FBP1 2022/4885 |
| US-11242554-B2 | Nitrodiarylethenes as fluorescence quenchers for nucleic acid probes | DNTT, NME2, DUT | TDP1 204/4885SRD5A2 1419/4885FBP1 2022/4885 |
| US-20180258471-A1 | NITRODIARYLETHENES AS FLUORESCENCE QUENCHERS FOR NUCLEIC ACID PROBES | DNTT, NME2, DUT | TDP1 204/4885SRD5A2 1419/4885FBP1 2022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.