SCHEMBL9134993

SCHEMBL9134993

CCCNC(=O)NS(=O)(=O)c1ccccc1-c1cccc(Cn2c(CCC)nc(SC)c2C(=O)O)c1

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 12/20 0.84
AGTR1 P30556 11/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7021272 0.91 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL9134474 0.91 AGTR2 (0.84) AGTR2AGTR1
SCHEMBL9409360 0.89 AGTR2 (0.67) AGTR2AGTR1
SCHEMBL7701057 0.87 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL8976602 0.87 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL8976768 0.86 AGTR2 (0.98) AGTR2AGTR1
Potassium SCHEMBL8976441 0.86 AGTR2 (0.98) AGTR2AGTR1
SCHEMBL16100919 0.86 AGTR2 (0.84) AGTR2AGTR1
SCHEMBL6544946 0.86 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL7022990 0.86 AGTR2 (0.89) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5468764-A Administering to a mammal an azole derivative HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-21 US disclosed
EP-0577023-A2 Angiotensin-II receptor-antagonists for the treatment of arrhythmices HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-05 EP disclosed