⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11760779 | 0.97 | SPHK2 (0.39) | — | |
| SCHEMBL12341240 | 0.83 | SPHK2 (0.48) | — | |
| SCHEMBL12341237 | 0.81 | SPHK2 (0.52) | — | |
| SCHEMBL28082072 | 0.78 | — | — | |
| SCHEMBL20198793 | 0.73 | — | — | |
| SCHEMBL179561 | 0.71 | — | — | |
| SCHEMBL17424318 | 0.71 | — | — | |
| SCHEMBL20198785 | 0.71 | — | — | |
| SCHEMBL5501237 | 0.71 | — | — | |
| SCHEMBL12619293 | 0.69 | SIGMAR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030912-B2 | Cationic steroidal antimicrobial compounds with urethane linkages | BRIGHAM YOUNG UNIVERSITY (US) | 2024-07-09 | — | — | US | disclosed |
| US-20230372362-A1 | METHODS FOR TREATING LUNG INFECTIONS AND INFLAMMATION | BRIGHAM YOUNG UNIVERSITY (US) | 2023-11-23 | — | — | US | disclosed |
| US-11739116-B2 | Methods for treating inflammation, autoimmune disorders and pain | BRIGHAM YOUNG UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
| US-11690855-B2 | Methods for treating lung infections and inflammation | BRIGHAM YOUNG UNIVERSITY (US) | 2023-07-04 | — | — | US | disclosed |
| US-20230050819-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2023-02-16 | — | — | US | disclosed |
| US-20210284629-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2021-09-16 | — | — | US | disclosed |
| US-20210238226-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2021-08-05 | — | — | US | disclosed |
| US-20210228723-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2021-07-29 | — | — | US | disclosed |
| US-10039285-B2 | Ceragenin particulate materials and methods for making same | BRIGHAM YOUNG UNIVERSITY (US) | 2018-08-07 | — | — | US | disclosed |
| US-20180169114-A1 | METHODS FOR REDUCING CELLULAR PROLIFERATION AND TREATING CERTAIN DISEASES | BRIGHAM YOUNG UNIVERSITY (US) | 2018-06-21 | — | — | US | disclosed |
| US-20130243842-A1 | COMPOSITIONS AND METHODS FOR TREATING BONE DISEASES AND BROKEN BONES | BRIGHAM YOUNG UNIVERSITY (US) | 2013-09-19 | — | — | US | disclosed |
| US-20130236619-A1 | ANTI-MICROBIAL FOOD PROCESSING COMPOSITIONS INCLUDING CERAGENIN COMPOUNDS AND METHODS OF USE | BRIGHAM YOUNG UNIVERSITY (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130109656-A1 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA, INC. | 2013-05-02 | — | — | US | disclosed |
| US-8324257-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2012-12-04 | — | — | US | disclosed |
| US-8268871-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20100331283-A1 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-7795282-B2 | Mitotic kinesin inhibitors and methods of use thereof | ARRAY BIOPHARMA INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20100041719-A1 | MITOTIC KINESIN INHIBITORS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2010-02-18 | — | — | US | disclosed |
| US-5472967-A | Angiotensin II antagonists | SYNTHELABO (FR) | 1995-12-05 | — | — | US | disclosed |
| EP-0500409-A1 | 4-Pyrimidinone derivatives, their preparation and their application in therapy | SYNTHELABO (FR) | 1992-08-26 | — | — | EP | disclosed |