SCHEMBL9135111

SCHEMBL9135111

O=c1ccsn1C(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
G6PD P11413 2/20 0.35
HPGD P15428 2/20 0.35
ALOX15 P16050 2/20 0.35
HSD17B10 Q99714 2/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KAT2B Q92831 7/20 0.34
EP300 Q09472 3/20 0.34
PIN1 Q13526 1/20 0.31
IDO1 P14902 1/20 0.31
TP53 P04637 1/20 0.30
HSP90AA1 P07900 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9246539 0.78 ALDH1A1 (0.34) ALDH1A1G6PDHPGDALOX15HSD17B10
SCHEMBL9318467 0.71 ALDH1A1 (0.34) ALDH1A1G6PDHPGDALOX15HSD17B10
SCHEMBL8592692 0.64 ALDH1A1 (0.41) ALDH1A1G6PDHPGDALOX15HSD17B10
SCHEMBL11283278 0.63 KAT2B (0.33) ALDH1A1G6PDHPGDALOX15HSD17B10
SCHEMBL79164 0.62 EP300 (0.44) ALDH1A1G6PDHPGDALOX15HSD17B10
SCHEMBL9132494 0.59 ALDH1A1 (0.33) ALDH1A1G6PDHPGDALOX15HSD17B10
SCHEMBL8594329 0.59 HSD17B10 (0.47) ALDH1A1G6PDHPGDALOX15HSD17B10
Calcium Chloride SCHEMBL21625034 0.57 INMT (0.45) ALDH1A1G6PDHPGDALOX15HSD17B10
SCHEMBL20718809 0.57
SCHEMBL9131360 0.54 ALDH1A1 (0.37) ALDH1A1G6PDHPGDALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5465527-A Landscaping border ABLE CORPORATION (US) 1995-11-14 US claimed
US-5465527-A Landscaping border ABLE CORPORATION (US) 1995-11-14 US disclosed
US-4396413-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1983-08-02 US disclosed
US-4325201-A BACTERICIDES, FUNGICIDES, PESTICIDES, AND SLIMICIDES; PAINTS; PRESERVATIVES ROHM AND HAAS COMPANY (US) 1982-04-20 US disclosed
US-4322475-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1982-03-30 US disclosed
US-4279762-A Cutting oils containing 3-isothiazolones as biocides ROHM AND HAAS COMPANY (US) 1981-07-21 US disclosed
US-4265899-A FUNGICIDES, BACTERICIDES ROHM AND HAAS COMPANY (US) 1981-05-05 US disclosed
US-4252694-A MICROBIOCIDES ROHM AND HAAS COMPANY (US) 1981-02-24 US disclosed
US-4243403-A BACTERICIDES, ACRYLIC POLYMERS, FUNGICIDES ROHM AND HAAS COMPANY (US) 1981-01-06 US disclosed
US-4241214-A BACTERICIDE, FUNGICIDE AND ALGAECIDE ROHM AND HAAS COMPANY (US) 1980-12-23 US disclosed
US-4150026-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1979-04-17 US disclosed
US-4105431-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1978-08-08 US disclosed
US-4062946-A 3-ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1977-12-13 US disclosed