Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Itaconate SCHEMBL9136633 | 0.90 | HSD17B10 (0.49) | HSD17B10ALOX15ALDH1A1TP53HIF1A | |
| Itaconate SCHEMBL6913753 | 0.88 | HSD17B10 (0.60) | HSD17B10ALOX15ALDH1A1TP53HIF1A | |
| Itaconate SCHEMBL10809656 | 0.87 | HSD17B10 (0.58) | HSD17B10ALOX15ALDH1A1TP53HIF1A | |
| Itaconate SCHEMBL11140682 | 0.87 | HSD17B10 (0.58) | HSD17B10ALOX15ALDH1A1TP53HIF1A | |
| Itaconate SCHEMBL28108621 | 0.85 | HSD17B10 (0.67) | HSD17B10ALOX15ALDH1A1TP53HIF1A | |
| Itaconate SCHEMBL6226414 | 0.84 | HSD17B10 (0.55) | HSD17B10ALOX15ALDH1A1TP53HIF1A | |
| SCHEMBL29602206 | 0.79 | ALDH1A1 (0.44) | HSD17B10ALOX15ALDH1A1TP53HIF1A | |
| Itaconate SCHEMBL11290331 | 0.79 | HSD17B10 (0.49) | HSD17B10ALOX15ALDH1A1TP53HIF1A | |
| Methacrylic Acid SCHEMBL9136233 | 0.79 | ALDH1A1 (0.47) | HSD17B10ALDH1A1TP53HIF1AMAPK1 | |
| Methacrylic Acid SCHEMBL28476192 | 0.79 | ALDH1A1 (0.47) | HSD17B10ALDH1A1TP53HIF1AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5410005-A | Comprising acrylic amide and ester copolymers and their salts, having carboxyl and sulfonic acid groups as well as fluoro | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| EP-0583918-A2 | Reflection preventing film and process for forming resist pattern using the same | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1994-02-23 | — | — | EP | disclosed |