Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 9/20 | 0.83 |
| ▸ | PDE2A | O00408 | 6/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.72 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.72 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.72 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.72 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.72 |
| ▸ | CD99 | P14209 | 1/20 | 0.71 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.70 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.70 |
| ▸ | CA5A | P35218 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14086559 | 1.00 | NT5E (0.83) | NT5EPDE2AADORA3ADORA2AADORA1 | |
| SCHEMBL14074374 | 1.00 | NT5E (0.83) | NT5EPDE2AADORA3ADORA2AADORA1 | |
| SCHEMBL24220725 | 0.93 | NT5E (0.78) | NT5EPDE2AADORA3ADORA2AADORA1 | |
| Clofarabine-5'-Triphosphate SCHEMBL8923866 | 0.92 | NT5E (0.77) | NT5EPDE2AADORA3ADORA2AADORA1 | |
| SCHEMBL8423402 | 0.91 | P2RY1 (0.83) | NT5EADORA3ADORA2AADORA1PDE4D | |
| SCHEMBL8423419 | 0.91 | P2RY1 (0.83) | NT5EADORA3ADORA2AADORA1PDE4D | |
| SCHEMBL10120960 | 0.91 | P2RY1 (0.83) | NT5EADORA3ADORA2AADORA1PDE4D | |
| SCHEMBL19100957 | 0.91 | NT5E (1.00) | NT5E | |
| SCHEMBL30563042 | 0.91 | NT5E (1.00) | NT5E | |
| SCHEMBL17304690 | 0.89 | PDE2A (0.74) | NT5EPDE2AADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5384310-A | Antitumor | SOUTHERN RESEARCH INSTITUTE (US) | 1995-01-24 | — | — | US | disclosed |