Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 7/20 | 0.83 |
| ▸ | P2RY11 | Q96G91 | 5/20 | 0.83 |
| ▸ | NT5E | P21589 | 3/20 | 0.82 |
| ▸ | CA5A | P35218 | 1/20 | 0.79 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.74 |
| ▸ | CA1 | P00915 | 1/20 | 0.74 |
| ▸ | CA2 | P00918 | 1/20 | 0.74 |
| ▸ | CA4 | P22748 | 1/20 | 0.74 |
| ▸ | CA9 | Q16790 | 1/20 | 0.74 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.73 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.73 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.73 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.73 |
| ▸ | LDHA | P00338 | 1/20 | 0.73 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.73 |
| ▸ | FBP1 | P09467 | 1/20 | 0.73 |
| ▸ | SRC | P12931 | 1/20 | 0.73 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.73 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.73 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423419 | 1.00 | P2RY1 (0.83) | P2RY1P2RY11NT5ECA5AADORA3 | |
| SCHEMBL10120960 | 1.00 | P2RY1 (0.83) | P2RY1P2RY11NT5ECA5AADORA3 | |
| SCHEMBL2025155 | 0.92 | P2RY1 (0.87) | P2RY1P2RY11NT5EADORA3CA1 | |
| SCHEMBL2025163 | 0.92 | P2RY1 (0.87) | P2RY1P2RY11NT5EADORA3CA1 | |
| SCHEMBL2027165 | 0.92 | P2RY1 (0.85) | P2RY1P2RY11NT5EADORA3SRC | |
| SCHEMBL2027164 | 0.92 | P2RY1 (0.85) | P2RY1P2RY11NT5EADORA3SRC | |
| SCHEMBL15082695 | 0.92 | P2RY1 (0.85) | P2RY1P2RY11NT5EADORA3SRC | |
| SCHEMBL29880723 | 0.92 | P2RY1 (0.85) | P2RY1P2RY11NT5EADORA3SRC | |
| SCHEMBL14074374 | 0.91 | NT5E (0.83) | P2RY1P2RY11NT5ECA5AADORA3 | |
| SCHEMBL9136027 | 0.91 | NT5E (0.83) | P2RY1P2RY11NT5ECA5AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579643-A1 | ATP ANALOGUES | FISONS plc (GB) | 1994-01-26 | — | — | EP | claimed |
| WO-1992017488-A1 | ATP ANALOGUES | FISONS PLC (GB) | 1992-10-15 | — | — | WO | claimed |
| EP-0508687-A1 | ATP analogues | Astra Pharmaceuticals Limited (GB) | 1992-10-14 | — | — | EP | claimed |
| US-5955447-A | ADMINISTERING AS ANTICOAGULANT; TREATING CARDIOVASCULAR DISORDERS | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-09-21 | — | — | US | disclosed |
| US-5721219-A | ANTICOAGULANTS | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-02-24 | — | — | US | disclosed |
| EP-0683789-B1 | N-ALKYL-2-SUBSTITUTED ATP ANALOGUES | ASTRA PHARMA PROD (GB) | 1997-11-05 | — | — | EP | disclosed |
| US-5654285-A | ADP and ATP analogues, process for making and administration to inhibit ADP-induced platelet aggregation | ASTRA PHARMACEUTICALS LIMITED (GB) | 1997-08-05 | — | — | US | disclosed |
| EP-0683789-A1 | N-ALKYL-2-SUBSTITUTED ATP ANALOGUES | Astra Pharmaceuticals Limited (GB) | 1995-11-29 | — | — | EP | disclosed |
| EP-0508687-B1 | ATP analogues | FISONS PLC (GB) | 1995-09-13 | — | — | EP | disclosed |
| WO-1994018216-A1 | N-ALKYL-2-SUBSTITUTED ATP ANALOGUES | ASTRA PHARMACEUTICALS LIMITED (GB) | 1994-08-18 | — | — | WO | disclosed |
| EP-0579643-A1 | ATP ANALOGUES | FISONS plc (GB) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992017488-A1 | ATP ANALOGUES | FISONS PLC (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0508687-A1 | ATP analogues | Astra Pharmaceuticals Limited (GB) | 1992-10-14 | — | — | EP | disclosed |