Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17671240 | 0.84 | NOTUM (0.53) | NOTUMCA1CA2TDP1CA12 | |
| SCHEMBL9096918 | 0.83 | NOTUM (0.65) | NOTUMCA1CA2TDP1CA12 | |
| SCHEMBL14293288 | 0.82 | NOTUM (0.59) | NOTUMCA1CA2TDP1CA12 | |
| SCHEMBL6011752 | 0.80 | NOTUM (0.61) | NOTUMCA1CA2TDP1CA12 | |
| SCHEMBL64502 | 0.80 | ALDH1A1 (0.72) | NOTUMCA1CA2TDP1CA12 | |
| SCHEMBL13645980 | 0.80 | NOTUM (0.61) | NOTUMCA1CA2TDP1CA12 | |
| SCHEMBL6932477 | 0.79 | NOTUM (0.59) | NOTUMCA1CA2TDP1CA12 | |
| SCHEMBL6932472 | 0.79 | NOTUM (0.59) | NOTUMCA1CA2TDP1CA12 | |
| SCHEMBL9134903 | 0.79 | NPC1 (0.52) | CA1CA2CA12CA7CA9 | |
| SCHEMBL4611523 | 0.77 | TSHR (0.63) | NOTUMCA1CA2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446062-A | Antiallergens, antiinflammatory agent | ABBOTT LABORATORIES (US) | 1995-08-29 | — | — | US | disclosed |
| US-5432194-A | Antiallergens, antinflammatory agents | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |
| US-5346914-A | Antiallergens, antiinflammatory agents | ABBOTT LABORATORIES (US) | 1994-09-13 | — | — | US | disclosed |