Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932477 | 0.88 | NOTUM (0.59) | NOTUMALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL1244024 | 0.86 | NOTUM (0.62) | NOTUMALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL2636334 | 0.86 | NOTUM (0.58) | NOTUMALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL7140538 | 0.86 | NOTUM (0.58) | NOTUMALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL2831110 | 0.85 | MLYCD (0.57) | NOTUMALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL7137753 | 0.85 | NOTUM (0.56) | NOTUMALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL23063887 | 0.83 | NOTUM (0.55) | NOTUMALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL9096918 | 0.81 | NOTUM (0.65) | NOTUMALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL9136121 | 0.80 | NOTUM (0.63) | NOTUMALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL6011752 | 0.79 | NOTUM (0.61) | NOTUMALDH1A1TSHRKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601180-B2 | Use for the dyeing with lightening effect of keratin substances of a composition comprising a fluorescent cyanine dye | L'OREAL S.A. (FR) | 2009-10-13 | — | — | US | disclosed |
| US-7601180-B2 | Use for the dyeing with lightening effect of keratin substances of a composition comprising a fluorescent cyanine dye | L'OREAL S.A. (FR) | 2009-10-13 | — | — | US | disclosed |
| US-20090049621-A1 | USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE | L'OREAL S.A. (FR) | 2009-02-26 | — | — | US | disclosed |
| US-20090049621-A1 | USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE | L'OREAL S.A. (FR) | 2009-02-26 | — | — | US | disclosed |
| EP-2018848-A2 | Hair composition comprising at least one fluorescent dye and at least one alkali hydroxide agent and method of simultaneous styling, dyeing and/or lightening. | L'Oreal (FR) | 2009-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090049621-A1 | USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE | KRT18, S100A4, S100P | NOTUM 2961/4885ALDH1A1 1895/4885TSHR 3685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.