Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216159 | 0.87 | ALOX5 (0.79) | ALOX5 | |
| SCHEMBL9219847 | 0.87 | ALOX5 (0.79) | ALOX5 | |
| SCHEMBL9219687 | 0.80 | ALOX5 (0.80) | ALOX5 | |
| SCHEMBL9256165 | 0.79 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9135113 | 0.78 | ALOX5 (0.80) | ALOX5 | |
| Zd-2138 SCHEMBL29372755 | 0.78 | ALOX5 (1.00) | ALOX5 | |
| Zd-2138 SCHEMBL1083603 | 0.78 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9022694 | 0.78 | ALOX5 (0.64) | ALOX5 | |
| SCHEMBL9135438 | 0.77 | ALOX5 (0.76) | ALOX5 | |
| SCHEMBL9217095 | 0.77 | ALOX5 (0.63) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462830-B1 | Cyclic ether derivatives | ZENECA LTD (GB) | 1995-10-18 | — | — | EP | claimed |
| US-5407945-A | Pyran derivatives and their use as inhibitors of 5-lipoxygenase | IMPERIAL CHEMICAL INDUSTRIES, INC. (GB) | 1995-04-18 | — | — | US | claimed |
| EP-0462830-A2 | Cyclic ether derivatives | ZENECA LIMITED (GB) | 1991-12-27 | — | — | EP | claimed |
| EP-0462830-B1 | Cyclic ether derivatives | ZENECA LTD (GB) | 1995-10-18 | — | — | EP | disclosed |
| US-5407945-A | Pyran derivatives and their use as inhibitors of 5-lipoxygenase | IMPERIAL CHEMICAL INDUSTRIES, INC. (GB) | 1995-04-18 | — | — | US | disclosed |
| US-5254581-A | Used in the treatment of various inflammatory and allergic diseases | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-10-19 | — | — | US | disclosed |
| EP-0462830-A2 | Cyclic ether derivatives | ZENECA LIMITED (GB) | 1991-12-27 | — | — | EP | disclosed |