Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366284 | 0.85 | ALOX5 (0.46) | ALOX5 | |
| SCHEMBL9022480 | 0.83 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9022697 | 0.83 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL9311516 | 0.79 | ALOX5 (0.37) | ALOX5 | |
| SCHEMBL9136252 | 0.78 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9256165 | 0.76 | ALOX5 (1.00) | ALOX5 | |
| SCHEMBL9138701 | 0.76 | ALOX5 (0.68) | ALOX5 | |
| SCHEMBL9138182 | 0.76 | ALOX5 (0.73) | ALOX5 | |
| SCHEMBL9135113 | 0.75 | ALOX5 (0.80) | ALOX5 | |
| Zd-2138 SCHEMBL1083603 | 0.75 | ALOX5 (1.00) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385679-B1 | Heterocyclic cyclic ethers with inhibitory activity on 5-lipoxygenase | ZENECA LTD (GB) | 1996-04-24 | — | — | EP | claimed |
| US-5196419-A | Lipoxygenase enzyme inhibitor | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | claimed |
| EP-0385679-A2 | Heterocyclic cyclic ethers with inhibitory activity on 5-lipoxygenase | ZENECA LIMITED (GB) | 1990-09-05 | — | — | EP | claimed |
| EP-0385679-B1 | Heterocyclic cyclic ethers with inhibitory activity on 5-lipoxygenase | ZENECA LTD (GB) | 1996-04-24 | — | — | EP | disclosed |
| US-5302603-A | Lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-04-12 | — | — | US | disclosed |
| US-5196419-A | Lipoxygenase enzyme inhibitor | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0385679-A2 | Heterocyclic cyclic ethers with inhibitory activity on 5-lipoxygenase | ZENECA LIMITED (GB) | 1990-09-05 | — | — | EP | disclosed |