Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACR | P10323 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817294 | 0.87 | SMN1; SMN2 (0.56) | ACRLMNARAB9ANPC1POLB | |
| SCHEMBL9133800 | 0.87 | ACR (0.51) | ACRLMNARAB9ANPC1POLB | |
| SCHEMBL9817266 | 0.86 | ACR (0.50) | ACRLMNARAB9ANPC1POLB | |
| SCHEMBL9134159 | 0.84 | NPC1 (0.50) | ACRLMNARAB9ANPC1POLB | |
| SCHEMBL9132730 | 0.82 | NPC1 (0.48) | ACRLMNARAB9ANPC1POLB | |
| SCHEMBL9510816 | 0.81 | MAPT (0.63) | ACRLMNARAB9ANPC1MAPT | |
| SCHEMBL9137610 | 0.77 | MEN1 (0.60) | RAB9ANPC1POLBMAPK1HTT | |
| SCHEMBL9512456 | 0.73 | GAA (0.71) | LMNARAB9ANPC1MAPTHTT | |
| SCHEMBL17740255 | 0.73 | MAPT (0.74) | ACRLMNARAB9ANPC1MAPK1 | |
| SCHEMBL27101154 | 0.73 | ACR (0.63) | ACRLMNARAB9ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464860-A | Antiepileptic agents | NOVAPHARME (FR) | 1995-11-07 | — | — | US | disclosed |
| US-5258397-A | FOR TREATMENT OF EPILEPSY; SIDE EFFECT REDUCTION | NOVAPHARME (FR) | 1993-11-02 | — | — | US | disclosed |